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1.
为了维护国家利益,保护国内产业,我国加入WTO后必须建立一套完备的反倾销法律。本文重点论述了我国反倾销法律在倾销行为、损害事实的认定和国内产业的界定等方面所作的修改,以及对新颁布的《中华人民共和国反倾销条例》进行完善的问题。  相似文献   

2.
为了维护国家利益 ,保护国内产业 ,我国加入WTO后必须建立一套完备的反倾销法律。本文重点论述了我国反倾销法律在倾销行为、损害事实的认定和国内产业的界定等方面所作的修改 ,以及对新颁布的《中华人民共和国反倾销条例》进行完善的问题。  相似文献   

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Deletion of self-reactive T cells before entry into the thymus medulla   总被引:23,自引:0,他引:23  
The thymus is important in the differentiation of bone marrow-derived precursor cells into functional T cells; humoral factors, as well as physical interactions with nurse cells, dendritic cells and epithelial cells, are thought to be instrumental in this process. Thymic lymphocytes mature during their migration from the cortical to the medullary region of the thymus, when they undergo phenotypic changes that include the acquisitions of T-cell antigen receptors, hormone receptors and differentiation antigens. Cortical T cells are thus mostly CD4+CD8+, whereas medullary T cells are either CD4+CD8- or CD4-CD8+. During this period T cells are subjected to two types of repertoire selection: all T cells recognizing self-MHC with low affinity may be preferentially amplified (positive selection), and in a second step T cells with high-affinity receptors for self-MHC determinants plus self antigens are eliminated (negative selection). We have described two monoclonal antibodies specific for the V beta 6 gene segment of the alpha/beta heterodimeric T-cell antigen receptor and have shown that most CD4+/V beta 6+ T cell recognize the Mlsa antigenic determinant but not Mlsb; similar results have been reported for V beta 8.1 and Mlsa. In both situations, tolerance to Mlsa correlated in an MHC-dependent fashion with absence of V beta 6 or V beta 8.1 T-cell antigen receptor expressing T cells in the periphery. We show here by immunostaining of thymus cryosections and cytofluorometric analysis that V beta 6-expressing cortical T cells are present at high density in both Mlsa and Mlsb mice, but do not enter the medullary region of Mlsa animals.  相似文献   

5.
化产业是一个新兴产业。相对西方发达国家来说,我国的化产业研究处于初始阶段。在加入WTO以后,如何应对WTO,加快发展我国的化产业,这是值得关注的课题。章联系我国化产业发展的实际,阐述如何正确界定化产业的概念,分析我国化产业在加入WTO后面临的发展机遇和严峻挑战,并提出了发展化产业的对策措施。  相似文献   

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Based on the recent advances of the research on the mechanism of HIV-1 infection, a novel model to elucidate the mechanism of HIV entry into the target cells is proposed and the perspective about the putative receptor is discussed in this review. Understanding of the crystal structure of HIV-1 transmembrane protein gp41 and the functions of HIV-1 receptor, co-receptor and the putative receptor will lead to developing effective HIV vaccine and anti-HIV drugs.  相似文献   

8.
Based on the recent advances of the research on the mechanism of HIV-1 infection, a novel model to elucidate the mechanism of HIV entry into the target cells is proposed and the perspective about the putative receptor is discussed in this review. Understanding of the crystal structure of HIV-1 transmembrane protein gp41 and the functions of HIV-1 receptor, co-receptor and the putative receptor will lead to developing effective HIV vaccine and anti-HIVdrugs.  相似文献   

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 埃博拉病毒是一类能够感染并引起人和灵长类动物发生埃博拉出血热的烈性囊膜病毒。发现近40年中,埃博拉病毒给人类生命带来了极大威胁。然而,目前人们对于埃博拉病毒的了解非常有限,尤其是病毒与其宿主细胞受体的结合机制和膜融合机制相关信息的缺失,使得针对埃博拉病毒的特效药物的设计和研发工作阻碍重重。本文综述了埃博拉病毒分类、形态、病毒蛋白和病毒生命周期,着重介绍了高福院士团队在埃博拉病毒入侵宿主细胞的分子机制研究中的成果。通过结构学手段解析了埃博拉病毒激活态囊膜糖蛋白GPcl与宿主细胞受体NPC1分子的复合物结构,从原子水平上阐明了埃博拉病毒与宿主细胞相互识别的机制,并在结构基础上对病毒的膜融合促发机制做出推测,提出以埃博拉病毒为代表的新的(第5种)囊膜病毒膜融合激发机制,为抗埃博拉病毒药物和疫苗的设计提供了结构基础。  相似文献   

11.
Ultrastructural analysis of toxin binding and entry into mammalian cells   总被引:10,自引:0,他引:10  
G L Nicolson 《Nature》1974,251(5476):628-630
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入世带来了中国会计环境的新变化。原有的会计高等教育中还存在与新经济环境不相适应的一些问题。会计教育工作者,应以入世为契机,抓住机遇,迎接挑战,采取积极有效的改革策略,使中国会计高等教育真正担负起培养综合素质会计人才的重任。  相似文献   

14.
针对加入WTO后国际国内人才需求的新情况,从分析当前我国经济与社会发展急需的人才结构入手,进而探索我国学校教育的应对策略,抓住机遇,办好具有中国特色的社会主义学校教育。  相似文献   

15.
加入WTO所面临的跨国并购   总被引:2,自引:0,他引:2  
结合我国现状 ,指出跨国公司在中国并购存在着有利因素和障碍 ,提出了相应的对策来确保跨国并购的正面效应 ,遏制负面效应 ,以便将跨国并购纳入我国经济发展的正常轨道 ,达到吸引外资和保护国内有效竞争的双重目的  相似文献   

16.
WTO对我国高职教育的影响是全面而深刻的,有直接和间接的,有近期和远期的,还有有利和不利的。我们必须树立新的教育观念,加强教学基本建设,尽快建立健全职教法律法规,主动迎接WTO对我国高职教育的挑战。  相似文献   

17.
Chfr defines a mitotic stress checkpoint that delays entry into metaphase   总被引:23,自引:0,他引:23  
Scolnick DM  Halazonetis TD 《Nature》2000,406(6794):430-435
Chemicals that target microtubules induce mitotic stress by affecting several processes that occur during mitosis. These processes include separation of the centrosomes in prophase, alignment of the chromosomes on the spindle in metaphase and sister-chromatid separation in anaphase. Many human cancers are sensitive to mitotic stress. This sensitivity is being exploited for therapy and implies checkpoint defects. The known mitotic checkpoint genes, which prevent entry into anaphase when the chromosomes are not properly aligned on the mitotic spindle, are, however, rarely inactivated in human cancer. Here we describe the chfr gene, which is inactivated owing to lack of expression or by mutation in four out of eight human cancer cell lines examined. Normal primary cells and tumour cell lines that express wild-type chfr exhibited delayed entry into metaphase when centrosome separation was inhibited by mitotic stress. In contrast, the tumour cell lines that had lost chfr function entered metaphase without delay. Ectopic expression of wild-type chfr restored the cell cycle delay and increased the ability of the cells to survive mitotic stress. Thus, chfr defines a checkpoint that delays entry into metaphase in response to mitotic stress.  相似文献   

18.
齐齐哈尔体育产业如何面对入世后的机遇与挑战   总被引:1,自引:0,他引:1  
通过对我国加入WTO后体育产业面临的机遇与挑战,分析了齐齐哈尔体育产业现状,并提出相应的对策。从而进一步提高齐齐哈尔市的体育产业竞争力。  相似文献   

19.
K L Gould  P Nurse 《Nature》1989,342(6245):39-45
The cdc2+ protein kinase (pp34) is found to be phosphorylated on tyrosine as well as serine and threonine residues in exponentially growing Schizosaccharomyces pombe. At mitosis, the level of pp34 phosphorylation on both threonine and tyrosine residues decreases. The single detectable site of tyrosine phosphorylation in pp34 has been mapped to Tyr 15, a residue within the presumptive ATP-binding domain. Substitution of this tyrosine by phenylalanine advances cells prematurely into mitosis, establishing that tyrosine phosphorylation/dephosphorylation directly regulates pp34 function.  相似文献   

20.
高职高专学生跨文化交际能力的培养   总被引:1,自引:0,他引:1  
加入WTO之后,对外交流与合作更加频繁。高职高专学生将面临更多的跨化实际的机遇。因此,习得跨化交际知识,了解其他国家化,培养跨化交际能力显得尤为重要。  相似文献   

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