Action du becaptan (β-mercapto-éthylamine) sur la radiosensibilité des cellules vaginales du rat femelle

Summary The authors studied the lesions observed in the vaginal smears of the rat after a local irradiation.They observed that an injection of cysteamine before the irradiation strongly diminishes the ratio of damaged cells.

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L. Darcis, Aspirant du F. N. R. S.     

L'influence de divers métabolites glucidiques sur l'intensité respiratoire du testicule de rat blanc

Zusammenfassung Glukose, Fruktose, Zitrat und Pyruvat erhöhenin vitro den Sauerstoffverbrauch des Rattenhodens; Saccharose ist wirkungslos.Glukose, Fruktose und Zitrat werden mit verschiedenen Geschwindigkeiten oxydiert, wobei dem Pyruvat eine katalytische Wirkung zukommt.     

Evolution et contrôle de l'activité de l'argininosuccinate synthétase,de l'argininosuccinase et de l'arginase du foie foetal de rat

Summary The activity of three urea-cycle enzymes, argininosuccinate synthetase, argininosuccinase and arginase have been studied in the ftal and new-born liver of rats. The activity increases with regularity between 17.5 days of pregnancy and birth in control foetuses. The lack of corticosteroid from 18.5 days of pregnancy decreases the activity of argininosuccinate synthetase. After administration of cortisol (hydrocortisone), to these 18.5-day-old foetuses lacking of corticosteroids, both activities of argininosuccinate synthetase and arginase are enhanced.

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Ce travail a été réalisé avec l'aide de la Délégation Générale à la Recherche Scientifique et Technique (contrat N^o 737 1148).     

Composition du suc de décongélation du muscle strié de la grenouille

Summary Because of cell membrane destruction, fluid escaping a muscle on thawing contains a large amount of proteins (myogen and globulin X). Whilst usual gradientsa, b, andc are present in the fluid, the gradientsd ande also occurring in extracts of unstimulated frog muscles are replaced by the gradientx already found in extracts of in N₂ exhausted muscles.     

Repercussions de l'hyperthyroïdie sur le contenu total en ADN du cervelet de rat âgé de 6 et 35 jours. Effets comparés de la LT3 et de la DLT4

Summary The total cerebellar proteins RNA and DNA contents from DLT4- and LT3-treated rats was studied at 6 and 35 days of age. The effect of injections of 5 g/j of DLT4 is comparable to that of 25 g of LT3 at birth, followed by 0.5 g every 2 days. On the other hand, injection of 0.5 g of LT3 every 2 days does not induce any significant modification of the total DNA contents in the cerebellum.     

Spécificité de l'antigène tumoral décelé dans le foie de rat porteur d'une tumeur de Walker

Summary By means of systematic comparative immunoelectrophoretic analysis, it has been shown that the antigenic material appearing in the liver of a Walker tumour bearing rat is highly specific to the tumour. In fact we have been unable to detect such an antigen either in embryonic neonatal, regenerating or in the liver of acute inflammations bearing rats.

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Travail subventionné par l'Institut du Cancer du Canada.     

Le degré de polymérisation de l'amylose,de l'amylopectine et du glycogène

Summary A colorimetric method based on the reducing power of the aldehydic end group has been developed in order to determine the M. W. of polysaccharides. It has been found that corn amylose contains chain molecules of much higher degree of polymerization than potato amylose.     

L'action du chlorure de lithium et du sulfocyanure de sodium sur la viscosité de la nucléohistone et des extraits d'embryons d'Amphibiens

Summary (1) LiCl increases the viscosity and decreases the rigidity of nucleohistone; NaSCN has opposite effects.(2) The effects of LiCl and NaSCN on the viscosity of amphibian embryo extracts, as observed byRanzi and his coworkers, seem to be due to the action of these salts on nucleohistone.     

Essais d'inhibition de l'action inflammatoire cutanée du chloroforme chez le rat

Summary (1)—In the rat, total extracts of cortex, cortisone and A.C.T.H. do not retard the fixation of a vital colorant at the level of a cutaneous zone irritated by chloroform.(2)—Phenergan prolongs the delay in the appearance of the blue.(3)—Sodium salicylate selectively inhibits the inflammatory cutaneous action of chloroform, even after adrenalectomy.     

Variation de la chaleur spécifique du caoutchouc en fonction de l'élongation

Summary The variation of the specific heat with extension was determined for several samples of rubber. Non-vulcanized rubber shows no change of the specific heat when extended between 0 and 300%. For vulcanized rubber, there is a very slight increase of the specific heat, proportional to the extension. For some samples a knee in the curve appears at about 200% (at room temperature), the linear increase of specific heat being about ten times higher for higher extensions. It is supposed that this sudden increase is related to the «heat of crystallization».     

Activité gonadotrope d'un extrait d'urines de femmes en ménopause

Summary An extract from pooled postmenopausal urine has been investigated for its gonadotrophic activity. Dose-response curves have been constructed for its total gonadotrophic activity (stimulation of estrogen secretion as reflected by the uterine weight increase in immature mice) and for its ICSH activity (stimulation of androgen secretion as reflected by the ventral prostate weight increase in hypophysectomised immature rats). In hypophysectomised immature rats, the extract produced repair of the interstitial cells of the testes and complete spermatogenesis. It contains, therefore, FSH as well as ICSH activity in comparable amounts, a fact which opens up interesting therapeutic possibilities.     

Activité gonadotrope d'un extrait d'urines de femmes en ménopause

Summary In agreement with earlier observations on hypophysectomized male rats, a purified extract from pooled menopausal urine has been shown to contain follicle-stimulating (FSH) as well as luteinizing (LH) activity. Its administration to immature hypophysectomized female rats increased ovarian and uterine weights and induced follicle growth and the formation of corpora lutea. If the activity of the extract is measured in standardized units by bioassay in intact female mice using the uterine weight, the dose needed for corpus luteum formation in the hypophysectomized female rat seems to be approximately ten times higher than the dose producing interstitial cell repair and complete spermatogenesis in the hypophysectomized male.

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2^e Communication: Effets sur les ovaires de rates impubères hypophysectomisées.     

L'activité du Centre de théories physiques de l'Institut Henri Poincaré pendant les dernières années

Sans résumé     

Activité staphylostatique de composés du groupe des benzophénarsazines

Summary It is shown that certain compounds belonging to the group of angular benzophenarsazines display a high specific bacteriostatic activity towardsMicrococcus pyogenes var.aureus. This biological property provides a further ground of similarity between these compounds and one of their structural analogues, 3,4–5,6-dibenzocarbazole.     

Etude de la consommation d'oxygène et de la teneur en acide désoxyribonucléique du foie à divers âges chez le rat

Summary The quantitative study of whole liver DNA and liver nuclei DNA at various ages, and the simultaneous study of oxygen uptake shows the following facts:(1) The rate of oxygen consumption to the fresh weight or to the DNA or to diploid chromosomes group is the same for the adult or the young aged 8 days. The values of oxygen consumption calculated for one cell or for one nucleus (taking notice of the fact that the mean level of liver nuclei DNA varies with the age) at 8 days is only the half of the adult value. Even at two months the value is 20% lower than in the adult.(2) In older animals there is a decrease of oxygen uptake which is more noticeable on a cellular scale than with the classical rate to fresh or dry weight. We affirm the fact that the diminution of the oxygen uptake of each cell is compensated by the increase of the number of cells.     

Action d'un inhibiteur de la carboanhydrase,l'acétazolamide,sur l'excitabilité du cortex,du thalamus et du rhinencéphale

Summary The electrical activity induced by stimulation of the cortex, diencephalon and rhinencephalon was studied in the rabbit under the influence of a carbonic anhydrase inhibitor, acetazolamide or Diamox. A significant decrease of the excitability was found in the diencephalon.The rapidity and the electivity of this action, as well as the blood pH variations simultaneously registered, suggest a specific inhibition of cerebral carbonic anhydrase by Diamox, although a participation of the metabolic acidosis cannot be fully excluded.     

Relations du « métabolisme respiratoire » des bactéries et du type de bactériophage avec l'activité de substances antiphages

Summary Quantitative determination of bacteriolysis with different T_1–7-phages confirms earlier observations that with substances inhibiting the action of T₁-phage the normal respiratory metabolism of the protected bacteria is quantitatively restored in every detail.With T₂-phage, showing a different respiratory course of bacteriolysis, no effect is obtained with the same substance, either on the respiration of the bacteria or on the typical course of respiration during bacteriolysis. The action of the phage inhibiting substance against T₁-phage is therefore an effect of definite specificity.     

De l'opportunité de quelques équations différentielles en vestibulométrie

Summary On the basis of wide experience in electronystagmography, the author has attempted to establish a characteristic and general relationship between the cupulo-ampullary system of the labyrinth underlining the mathematical parallelism with the cochlear system. At the same time, some partial physico-mathematical analogies, which were expressed concerning the same subject, are criticized.