共查询到20条相似文献,搜索用时 15 毫秒
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摘要: 目的 对高等医学院校实验动物设施状况、人员配置、服务内容和管理现状进行调查。方法 设计调查表,对国内 10 所高等医学院校实验动物中心进行问卷调查,调查内容包括学校规模、设施状况、人员配置及经费来源、服务内容、管理模式等方面。结果 40% 高等医学院校的动物设施不能满足需求; 在设施运行经费来源方面,50%实验动物中心的经费来源于拨款和消耗自筹; 服务内容已从传统的动物饲养向实验辅助、委托试验发展,80% 实验
动物中心能提供病理技术服务,70% 实验动物中心能制作转基因动物; 所有调查的实验动物中心都要求实验动物从业人员必须经过培训并取得证书; 在实验管理方面,80% 实验动物中心是针对 PI 团队进行统一管理。结论 高等医学院校实验动物中心服务内容和管理水平较高,但相关硬件设施建设方面仍需加强。 相似文献
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为了进一步推动高科技生物技术的发展 ,北京市在“二四八”工程中确立了屏障系统运行管理培训基地建设的计划。这是推动我国实验动物质量保证体系建立的重要内容 ,是使实验动物工作尽快与国际规范接轨的一项重要措施。几年来 ,北京市在实验动物标准化设施建立和规范化管理等方面已取得了长足发展。但实验动物从业人员培训工作相对滞后 ,培训制度和相应的管理体系还需完善 ,屏障系统运行管理的统一培训尚未开始 ,致使新建设施、设备使用率低 ,运行质量不高 ,严重制约了北京市实验动物质量体系的建立和实验动物科学的发展。北京市是全国实验动物科学发展的中心地区 ,在人才、设施等各方面具有优势。在全国率先开展“屏障系统运行管理培训”可以在全国实验动物界产生示范效应 ,将推动我国实验动物质量保证体系的建立。“屏障系统运行管理培训基地建设”将更好地为实验动物科学在岗的各层次人员的培训提高提供规范持久的学习和实习场地。 相似文献
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熊洪斌 《黔西南民族师范高等专科学校学报》2015,(1):110-113
孙竹雅所著《学书枝言》,能够抓住书学的重点和难点,以简炼而优美的文字,由浅入深,娓娓道来,解决了许多实际的疑难问题。又能够深入浅出、生动形象地说明了众多的书学问题,长善救失,时现警策精辟之论,金针度人,开启其"帖学"门庭。文章前后照应贯通,结构严谨,转换过渡,环环紧扣;通篇则文法多变,摇曳生姿。读来引人入胜,思之令人解颐。长语短句,错综杂出;或取譬而巧喻,或言简而意丰;用字考究,音调铿锵,诵之则朗朗上口,咏之而荡气回肠。从文章写作的角度看,《学书枝言》一卷颇有其文法上的艺术特点,值得今人学习与借鉴。 相似文献
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《大庆师范学院学报》2015,(4):100-104
站话中的"子"缀词语与周边黑龙江方言及普通话相比,除了具有共同特征外,还表现出一定的差异性。从构成上来看,站话中"子"缀词语的词根无论音节数量还是词性都非常丰富,构成了数量众多的"子"缀词语;从功能和语义特征上来看,站话中"子"缀构词能力更强,可以构成一定数量的动词,而且虚化程度更高,语义色彩更加轻淡。 相似文献
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方灵芝 《新乡学院学报(自然科学版)》2008,(2)
监狱是《双城记》里的一个重要主题,不管是有形的还是无形的。主人公在监狱里饱受着肉体T精神上的折磨。监狱对故事情节的发展也起着非常重要的作用。列出了下列监狱,有形的:巴士底狱,拉福斯,台尔森银行——巴士底狱的翻版。无形的:曼内特的精神监狱;德伐日夫人的复仇监狱;法国人民的生活监狱;达尔内的守愿监狱;卡尔顿的情感监狱。浅探了上述监狱对故事情节的发展所起的伏笔作用,各种监狱都为后来故事情节的发展铺平了道路。 相似文献
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The electro-deoxidation of V2O3 precursors was studied. Experiments were carried out with a two-terminal electrochemical cell, which was comprised of a molten
electrolyte of CaCl2 and NaCl with additions of CaO, a cathode of compact V2O3, and a graphite anode under the potential of 3.0 V at 1173 K. The phase constitution and composition as well as the morphology
of the samples were studied by X-ray diffraction (XRD) and scanning electron microscopy (SEM). 3 g of V2O3 could be converted to vanadium metal powder within the processing time of 8 h. The kinetic pathway was investigated by analyzing
the product phase in samples prepared at different reduction stages. CaO added in the reduction path of V2O3 formed the intermediate product CaV2O4. 相似文献
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LIU Yingjuan YANG Zhanqiu DENG Haiying XIAO Hong QU Chunfeng 《武汉大学学报:自然科学英文版》2007,12(6):1143-1147
A water-soluble substance was extracted from the Chinese herb, Alternantheraphiloxcroides with hot water and alcohol. Aliquots of this initial extract were further fractionated by treatment with ether, ethyl acetate and alcohol respectively. The four extracts were assayed for anti-viral activity against three serum, Hantaan virus 114 (HV114), HV435 and A9 strains. Results show that the four extracts are capable of inhibiting Hantaan virus propagation, of which extract No. 1 has the best efficiency. The three dosage of extract No. 1, which are used upon three Hantaan virus serum IC50, are 153, 157, 154 μg/mL. New-born mice were made to be infected with HV114 and then fed in vivo with extract No.l on the 3rd, 10th and 14th days after being infected by the virus. The treatment continued for 8 days with a dosage of 2.5 g/kg. Result shows that survival rates of mice were 75%, 50% and 0, respectively. The median time to death (MTDs) of the three groups were 37, 30, 23 days. 相似文献
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YANG Kong WEI Jie WANG ChaoYuan LI YuBao 《科学通报(英文版)》2007,52(2):267-271
When bioactive materials are implanted in vivo, a bone-like apatite layer can be found on their surfaces, which is critical to the establishment of bone-bonding between materials and living tissues. In this study, bone-like apatite formation in vitro and in vivo on surface of nano apatite/polyamide (n-HA/PA66) composite was investigated, and the interface between the implanted composite and surrounding bone tissue of rabbit were also examined. The results revealed that in both simulated body fluids (SBF) and dorsal muscles of rabbit, bone-like apatite could form on the biocomposite surface. When the samples were implanted in cortical bone, they combined directly with the natural bone without fibrous tissue in-between. The results showed that the n-HA/PA66 biocomposite had excellent bioactivity, which might be a good candidate for bone defect replacement. 相似文献
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LIU Fang ZHANG XiangQian ZHANG ZeMin CHEN ZhaoGui ZHU HaiTao WANG Jiang ZHANG JingLiu ZHANG GuiQuan 《科学通报(英文版)》2007,52(20):2789-2796
Insertional mutagenesis based on maize Activator/Dissociator (Ac/Ds) transposons is becoming a ma- jor approach used to produce a saturated mutant collection in rice. In this research, Ds-T-DNA trans- formed homozygotes were crossed with Ac-T-DNA transformed homozygotes in order to establish an Ac/Ds transposon system in rice. The successive investigation of Ds transposition from F1 to F5 gen- erations indicated that the frequencies of germinal transposition increased over successive genera- tions and reached 54.2% in F3 generation. The Ds transposition pattern revealed that a Ds transposition induced an approximately 170-bp deletion of T-DNA sequence and another Ds transposition carried a 272-bp T-DNA sequence. Using thermal asymmetric interlaced PCR (TAIL-PCR), some flanking se- quences of the Ds element were amplified. Analyses of 17 Ds-flanking sequences showed that five Ds were inserted into gene regions. The Ds could transpose not only to the linked sites but also to the unlinked sites. The frequency of inter-chromosomal transposition of Ds was 33.3%. 相似文献
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