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1.
Summary A comparison of pupation-temperature range was made in the laboratory on a temperature gradient (3–38°C) using 12 species ofDrosophila representing four species groups and four different ecological backgrounds (temperate-montane forest:virilis group; desert;repleta group; cosmopolitan:melanogaster group; tropical forest:willistoni group). Within groups, differences are found which usually reflect species' distributions. Comparisons of species' mating-, oviposition- and pupation-temperature ranges reveal that pupation most-often occurs at temperatures beyond those for mating and oviposition. Each species reflects a different combination of temperature effects. Individual species have different temperature-limits for mating, oviposition and pupation. Temperatures permissive for one response are not predictive of limits on other responses. Among species, temperature can affect a particular response differently. Within groups, species differences can be at high and/or low temperatures for any response, and temperature effects among closely related species can manifest themselves in one, or any combination of responses. One cannot predict which responses will be most and least limited, or at which end of the temperature scale a response will be most limited. Among groups,common, but notabsolute temperature ranges generally correspond to the geographic distributions and ecological backgrounds of the species triads. The evaluation of temperature effects on species, based on a single activity, may not be adequate for predicting adaptive strategies. 相似文献
2.
M. D. Moltó L. Pascual M. J. Martínez-Sebastián R. de Frutos 《Cellular and molecular life sciences : CMLS》1993,49(1):54-56
The effect of heat shock on protein synthesis in three relatedDrosophila species belonging to theobscura group was analyzed on SDS-acrylamide gels. Four major heat shock proteins (hsps) were found in these species, in which synthesis reaches a maximum at 34°C. Although the higher molecular weight proteins are conserved, differences in size were found for the small hsps in these species. By means of in situ hybridization usingD. melanogaster probes for the small hsp genes, it was inferred that the small hsp genes of theobscura group species are clustered at the 27A locus in all three species. 相似文献
3.
Pinho SS Seruca R Gärtner F Yamaguchi Y Gu J Taniguchi N Reis CA 《Cellular and molecular life sciences : CMLS》2011,68(6):1011-1020
Several mechanisms have been proposed to explain the E-cadherin dysfunction in cancer, including genetic and epigenetic alterations.
Nevertheless, a significant number of human carcinomas have been seen that show E-cadherin dysfunction that cannot be explained
at the genetic/epigenetic level. A substantial body of evidence has appeared recently that supports the view that other mechanisms
operating at the post-translational level may also affect E-cadherin function. The present review addresses molecular aspects
related to E-cadherin N-glycosylation and evidence is presented showing that the modification of N-linked glycans on E-cadherin can affect the adhesive function of this adhesion molecule. The role of glycosyltransferases
involved in the remodeling of N-glycans on E-cadherin, including N-acetylglucosaminyltransferase III (GnT-III), N-acetylglucosaminyltransferase V (GnT-V), and the α1,6 fucosyltransferase (FUT8) enzyme, is also discussed. Finally, this
review discusses an alternative functional regulatory mechanism for E-cadherin operating at the post-translational level, N-glycosylation, that may underlie the E-cadherin dysfunction in some carcinomas. 相似文献
4.
B. Banerjee 《Cellular and molecular life sciences : CMLS》1976,32(8):993-994
Summary Biological and statistical aspects of the application of variance to mean ratio to describe spatial distribution of animals are discussed. It is shown that the parameterb inTaylor's power laws
2=a m
b shows intra-specific variation depending on the distribution of the constituent units of the population.a andb are only parameters of a very empirical way of describing the relation between variance and mean, which itself is an indicator for spatial distribution. Hence,a andb depend on the distribution behaviour of the animals, and not vice versa.Acknowledgments: The work was developed whilst I was at the Department of Entomology, University of Nairobi. I am grateful to ProfessorT. R. Odhiambo for his interest. I thank the referee for comments. 相似文献
5.
M. E. Scarazzatti R. Bonatelli Jr. J. L. Azevedo 《Cellular and molecular life sciences : CMLS》1979,35(3):307-308
Summary A mutant ofAspergillus nidulans resistant to ethidium bromide was isolated and the semi-dominant gene responsible for this resistance was allocated on linkage group II at 17.42±3.05 units of recombination from thewA3 gene. The gene also confers cross-resistance to acriflavin, malachite green and crystal violet. It was also shown that riboflavin is antagonistic to the toxic effect of ethidium bromide, at certain concentrations. The mechanisms which could be responsible for the toxic effect of this drug are discussed and compared with those of acriflavin. The use of theEtb
1 gene in genetical analysis through the parasexual cycle is suggested.Acknowledgements. The authors are thankful to the National Council for the Development of Science and Technology (CNPq) for financial support through PIG-SIP 04/053 FAPESP. 相似文献
6.
Summary Measurements of the asphyxial oxygen level forRhinomugil corsula, Tilapia mossambica, Puntius sarana andCarassius auratus at 30 and 35°C revealed that at 35°C the lethal oxygen level was higher forT. mossambica andP. sarana and lower forR. corsula, but it remained the same forC. auratus at 30 and 35°C.
From a thesis (M.P.M.) approved for the degree of Doctor of Philosophy, Madurai Kamaraj University, madurai, India.
We wish to express our thanks to Prof. S. Krishnaswamy for providing facilities and to Dr S.V. Job for suggestions. 相似文献
7.
Summary In order to evaluate the effect of several intercalating compounds on crossing-over inDrosophila melanogaster females, acridine orange, acriflavine, chloroquine, ethidium bromide and quinacrine were fed separately to larvae ofy ct f/+++ genotype. Our results show that acridine orange, acriflavine and ethidium bromide increase significantly the recombination frequency at thect-f region and support the view that, for intercalating agents, there is a relationship between clastogenic activity and female recombination induction. 相似文献
8.
L. S. Ciereszko Y. Gopichand F. J. Schmitz W. P. Schneider G. L. Bundy 《Cellular and molecular life sciences : CMLS》1985,41(1):37-38
Summary The lipid fraction, 17%, of air-driedPlexaura homomalla formakükenthali, collected in the Caribbean at Puerto Rico, yielded 50% of its weight as the mammalian prostaglandin (15S)-PGA2 methyl ester. The freeze-dried gorgonian yielded (15S)-PGA2 largely as the acetate of the methyl ester. (15S)-PGA2 was also obtained from material collected at St. Croix and at South Caicos. Field observations indicate thatPlexaura kükenthali may be a species separate fromPlexaura homomalla and that it is abundant on some shallow water reefs in the Caribbean. Prostaglandins could not be detected in the lipid fraction of eggs isolated fromPlexaura homomalla (Esper) formahomomalla.Acknowledgments. We gratefully acknowledge support from the Office of Sea Grant, NOAA, Department of Commerce (Grant 047-158-44067), and the use of facilities at the Isla Mayagues Marine Laboratory of the University of Puerto Rico, Mayaguez, the West Indies Laboratory of Fairleigh Dickinson University at St. Croix, U.S.V.I., and the Marine-Biologisch Instituut at Curacao. Special thanks to Dr. F.M. Bayer, Curator, Department of Zoology, National Museum of Natural History-Smithsonian Institution for checking identity of gorgonians used in this study. 相似文献
9.
The nutritional condition of the shanny (Lipophrys pholis, Teleostei, Blenniidae), an intertidal fish, is affected by the shore level on whihc it dwells. Depending on the altitude within the intertidal, zone access to food is restricted for a certain time. A progressive decrease in the feeding time for an individual remaining on an increasingly higher shore level leads to a poorer nutritional condition compared to an individual staying at a lower shore level. Trade-off mechanisms between the feeding time and competition for space and/or predation pressure seem to be responsible for the still high abundance ofL. pholis on the upper shore. Possible consequences for growth and reproduction as well as distribution patterns are discussed. 相似文献
10.
C. A. Clarke A. Cronin W. Francke P. Philipp J. A. Pickett L. J. Wadhams C. M. Woodcock 《Cellular and molecular life sciences : CMLS》1996,52(6):636-638
It has been suggested that a common sex pheromone composition may account for interspecific sexual interactions observed with certain moths in the Arctiidae. In this study, it is demonstrated that the sex pheromones released by females of the Scarlet Tiger Moth,Callimorpha dominula L., and the Cinnabar Moth,Tyria jacobaeae L., have similar activities and elute at the same retention time on analysis by coupled gas chromatography (GC)-electrophysiology with males from each species. Peak enhancement on GC, chiral GC and coupled GC-mass spectrometry using authentic compounds show that the sex pheromone for bothC. dominula andT. jacobaeae is (3Z,6Z,9S,10R)-9,10-epoxyheneicosa-3,6-diene. 相似文献
11.
This paper presents a comparative analysis of the sources of error in forecasts for the UK economy published over a recent four-year period by four independent groups. This analysis rests on the archiving at the ESRC Macroeconomic Modelling Bureau of the original forecasts together with all their accompanying assumptions and adjustments. A method of decomposing observed forecast errors so as to distinguish the contributions of forecaster and model is set out; the impact of future expectations treated in a ‘model-consistent’ or ‘rational’ manner is specifically considered. The results show that the forecaster's adjustments make a substantial contribution to forecast performance, a good part of which comes from adjustments that bring the model on track at the start of the forecast period. The published ex-ante forecasts are usually superior to pure model-based ex-post forecasts, whose performance indicates some misspecification of the underlying models. 相似文献
12.
《Annals of science》2012,69(3):307-333
Summary Pierre-Joseph Macquer (1718–1784) is well known as one of the major chemists in the eighteenth century as a theoretician and a teacher. He is also known for his works on dyeing. This paper presents a new face of Macquer. He proposed a theory on mordants in dyeing as early as 1775. Besides his activity at the Académie des sciences, he played an important role in Government as the commissioner of dyeing from 1766 where he established close links with artisan inventors. Académicien chimiste at the royal Manufactory of Sèvres from 1757, he was also the inventor of French porcelain. His notebooks show his organization, method, courage, passion and obstinacy in the search for the paste for hard porcelain. He also proposed an interpretation of its formation. Macquer was both a theoretician and a practical expert in dyeing as well as in porcelain making. He managed to bridge the gap between science and art. 相似文献
13.
Summary At Bundi (Rajasthan, India), aPinus roxburghii tree has been observed to develop green, needle-like, spirallyarranged, elongated, foliar leaves on long shoots. Such foliar leaves are not reported onPinus plants except at the seedling stage.Grateful thanks to Dr Elbert L. Little of the US Department of Agriculture (Forest Service) for suggestions. 相似文献
14.
J. J. Bull 《Cellular and molecular life sciences : CMLS》1985,41(10):1285-1296
Summary Theories on the evolution of sex determining mechanisms are reviewed for male and female heterogamety, environmental sex determination, and briefly, haplo-diploidy and hermaphroditism. Because of their discrete and well-defined nature, sex determining mechanisms lend themselves to three types of evolutionary questions:what variety occurs and might be expected but does not occur,how do changes occur from one mechanism to another, andwhy do certain changes occur? All three approaches were illustrated for these different sex determining mechanisms. A generality emerging from these studies is that, at the level of selection on the sex ratio, there are no intrinsic problems in evolving from one sex determining mechanism to another: straightforward transitions between different mechanisms exist under various conditions. 相似文献
15.
E. Christians E. Michel J.-P. Renard 《Cellular and molecular life sciences : CMLS》1997,53(2):168-176
Heat shock genes are found in all organisms, and synthesis of heat shock proteins is induced by various stressors in nearly
all the cells forming these organisms. However, a particular situation is noticed for hsp70 genes in mouse embryos at the beginning of their development. First, spontaneous expression of hsp70 is observed at the onset of zygotic genome activity. Second, inducible expression is delayed until morula or early blastocyst
stages. A better understanding of both these points depends on a more careful analysis of hsp70 expression in relation to their major regulators, the heat shock factors. In this review, we will see how the development
of the preimplanta tion embryo highlights the complexity of heat shock gene regulation involving trans-cis interactions and the cellular and nuclear environment. 相似文献
16.
In October 1924, The Physical Review, a relatively minor journal at the time, published a remarkable two-part paper by John H. Van Vleck, working in virtual isolation
at the University of Minnesota. Using Bohr’s correspondence principle and Einstein’s quantum theory of radiation along with
advanced techniques from classical mechanics, Van Vleck showed that quantum formulae for emission, absorption, and dispersion
of radiation merge with their classical counterparts in the limit of high quantum numbers. For modern readers Van Vleck’s
paper is much easier to follow than the famous paper by Kramers and Heisenberg on dispersion theory, which covers similar
terrain and is widely credited to have led directly to Heisenberg’s Umdeutung paper. This makes Van Vleck’s paper extremely valuable for the reconstruction of the genesis of matrix mechanics. It also
makes it tempting to ask why Van Vleck did not take the next step and develop matrix mechanics himself.
This paper was written as part of a joint project in the history of quantum physics of the Max Planck Institut für Wissenschaftsgeschichte and the Fritz-Haber-Institut in Berlin. 相似文献
17.
Carol Taylor West 《Journal of forecasting》1996,15(5):369-383
System-based combination weights for series r/step-length h incorporate relative accuracy information from other forecast step-lengths for r and from other series for step-length h. Such weights are examined utilizing the West and Fullerton (1996) data set-4275 ex ante employment forecasts from structural simultaneous equation econometric models for 19 metropolitan areas at 10 quarterly step-lengths and a parallel set of 4275 ARIMA forecasts. The system-based weights yielded combined forecasts of higher average accuracy and lower risk of large inaccuracy than seven alternative strategies: (1) averaging; (2) relative MSE weights; (3) outperformance (per cent best) weights; (4) Bates and Granger (1969) optimal weights with a convexity constraint imposed; (5) unconstrained optimal weights; (6) select a ‘best’ method (ex ante) by series and; (7) experiment in the Bischoff (1989) sense and select either method (2) or (6) based on the outcome of e experiment. Accuracy gains of the system-based combination were concentrated at step-lengths two to five. Although alternative (5) was generally outperformed, none of the six other alternatives was systematically most accurate when evaluated relative to each other. This contrasts with Bischoff's (1989) results that held promise for an empirically applicable guideline to determine whether or not to combine. 相似文献
18.
Urochordates carry multiple genes for goose-type lysozyme and no genes for chicken- or invertebrate-type lysozymes 总被引:1,自引:1,他引:0
Nilsen IW Myrnes B Edvardsen RB Chourrout D 《Cellular and molecular life sciences : CMLS》2003,60(10):2210-2218
Genome clones and expressed sequence tags (ESTs) from the ascidian Ciona intestinalis and from the larvacean Oikopleura dioica were analysed for the presence of lysozyme-encoding genes. Two genes were found to potentially code for goose-type lysozymes in Oikopleura, while three or possibly more g-type proteins form the lysozyme complement of C. intestinalis, and at least one of these genes from each species is expressed based on EST data. No genes for chicken- or invertebrate-type lysozymes were found in either urochordate species. Consistent with this finding, extracts of Oikopleura animals possessed hydrolysing activity on bacterial cell walls, and this activity was not inhibited in the presence of a known inhibitor of chicken-type lysozyme. A wide range of isoelectric points for the predicted lysozymes from Ciona (pI 4.4, 6.4 and 9.9) and from Oikopleura (pI 5.0 and 8.0) suggests tissue-specific adaptations as well as specific functional roles of the lysozymes. Comparisons of gene structures, encoded sequences, cysteine residue content and their positions in the proteins indicate that the g-type lysozymes of Ciona intestinalis are more closely related to those of vertebrates than are the g-type lysozymes of Oikopleura. Multiple genes from each species may result from separate and lineage-specific duplications followed by functional specialisation.Received 29 June 2003; received after revision 24 July 2003; accepted 29 July 2003 相似文献
19.
Summary A mutant strain ofEscherichia coli K-12 lacking phosphomethylpyrimidine kinase activity was produced from the polyauxotrophic female strain, JC1552. The locus of its lesion, for which we propose the designationthiD, was mapped at about 46 min on the chromosome. 相似文献
20.
Antifungal properties of taxol and various analogues 总被引:2,自引:0,他引:2
D. H. Young E. L. Michelotti C. S. Swindell N. E. Krauss 《Cellular and molecular life sciences : CMLS》1992,48(9):882-885
The antimitotic agent taxol was tested for toxicity towards fungi from different taxonomic groups and found to be particularly active against oomycete fungi. In germinating zoospore cysts of the oomycetePhytophthora capsici the mechanism of action of taxol was shown to involve inhibition of mitosis, presumably resulting from an effect on microtubules. Various taxol analogues with deleted A-ring C-13 side chain substituents were tested for toxicity towardsP. capsici andAphanomyces cochlioides to provide insight into structural features required for activity. The importance of the side chain was shown by the much lower activity as compared to taxol of analogues lacking all or part of the side chain. The effect of stereochemistry at the C-2 position on fungitoxicity towards oomycetes was similar to that reported previously on mammalian microtubule assembly. 相似文献