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Conclusions The decrease of circulating blood volume, resulting in oligemic hypotension, may evoke in anaesthetized cat the active constrictory coronary vessel responses of 2 types, one occuring immediately after start of the hypotension and the other having a significantly prolonged latency.
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-Spermophilus brunneus . , 13 18 ,S. brunneus S. townsendii mollis (2n=38) , , ; ;S. brunneus . S. brunneus , Spermophilus.

Supported by National Science Foundation Grants No. GB32114X and No. GB 29131X, and the Sprague Foundation. We thankD. Pozin for technical assistance.  相似文献   

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. : (. . 59,000–61,000 ), (34,000–38,000) (15,000–18,000).  相似文献   

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Conclusion Changes of the vessel capacity resulted from the pressor synocarotid reflexes, intestinal chemoreflexes and reflexes from the right atrium or ventricle and electric stimulation of the somatic nerve afferents can be either similarly or differently directed as compared with the responses of the resistance vessels.
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Zusammenfassung Die Bildung von 11-Carboxy-3, 11, 17-trihydroxy-13-C-nor-5-androstan 11a,17-Lakton aus 3, 17-Diacetoxy-11-hydroxy-12-oxo-5-9(11)-androsten wird beschrieben. Der Mechanismus und die Stereochemie dieser Umwandlung (Retro-Aldolkondensation und Benzilsäureumlagerung) wird diskutiert.  相似文献   

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Summary The effect of 5-androstan-17-ol-3-one (DHT) and of 5-androstan-3,17-diol (3-diol) on stress-induced prolactin hypersecretion has been investigated in castrated female rats. A 6-day treatment with 2 mg of these steroids does not inhibit the ether-induced increase in prolactin serum levels.  相似文献   

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Tumor necrosis factor (TNF) was repeatedly microinfused into the lateral ventricle of guinea pig brains at a dose of 200 ng, 4 times within 150 min, at intervals of 3 days. In comparison to guinea pigs infused with solvent according to the same time schedule, the animals responded to TNF with pronounced fevers. The quantity of the fever response was the same after each of the 4 microinfusions of TNF. Three days after the last infusion of TNF or solvent all animals received an intramuscular injection of bacterial lipopolysaccharide (LPS). The fever in response to LPS was the same in both groups. Thus, the reported development of tolerance to repeated systemic administration of TNF1–3 does not develop inside the blood-brain barrier. Also, the febrile response to LPS is not influenced by repeated central pre-treatment with TNF, whereas repeated peripheral treatment does have an effect.  相似文献   

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Summary The effect of refeeding of mice after a fasting period on the uptake of 3H-thymidine and on mitotic activity in the gall bladder epithelium was studied by histoautoradiography. A significant increase in both DNA synthesis and mitotic activity was observed after 12 h of refeeding.Acknowledgments. This work was supported by the Fonds voor Geneeskundig Wetenschappelijk Onderzoek and by the Algemeene Spar-en Lijfrentekas.  相似文献   

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