氢键系统中两类子晶格非简谐势作用下的孤子对

以氢键系统中的二分量孤子模型为基础,研究了两类不同子晶格中非简谐势作用下的孤子对的运动,获得了源子非简谐性下孤子对的非对称解,并得出了孤子对的能量,有效质量和电荷密度。     

Local destabilisation of a DNA double helix by a T--T wobble pair.

Nuclear magnetic resonance is a technique which permits direct observation of the Waton--Click hydrogen-bonded ring imino protons (guanine N1H and thymine N3H). As the formation and disruption of hydrogen bonds of double-helical RNA and DNA structures are key events during various biological processes, NMR thus provides a useful tool for studying the fluctuational mobility of the individual base pairs. Indeed, several NMR studies of oligo- and polynucleotides have been carried out to probe the structure and dynamics of nucleic acids in solution (for a review see ref. 1). The present study constitutes the first part of our attempt to assess the influence of non-complementary base pairs on the stability of nucleic acid double helices. We report the spectral assignment and temperature-dependent NMR profiles of the hydrogen-bonded imino protons of the two DNA fragments shown in Fig. 1. The assignment is based solely on experimental grounds using the principle of chemical modification. It will be demonstrated that the introduction of a non-complementary (wobble) base pair in a DNA duplex introduces an extra melting site in addition to the sequential melting which starts with the terminal base pairs in the double helix structure.     

The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes

Tissue position-dependent or address-dependent expression of cell adhesion molecules has been proposed to play a part in cellular positioning in a variety of systems, for example during neural development, the metastasis of neoplasms, and the tissue-specific homing of lymphocytes. The extravasation of blood-borne lymphocytes is regulated by interactions with the endothelium of specialised venules, such as the high endothelial venules (HEV) in organized lymph nodes and mucosal lymphoid tissues. At least three separate lymphocyte-HEV recognition systems have been described, one mediating tissue-selective lymphocyte interactions with HEV in peripheral lymph nodes, another in mucosal lymphoid organs, and a third in inflamed synovium. We have previously identified a tissue-specific 'vascular addressin' in the mouse which is selectively expressed by venules mediating lymphocyte-homing into mucosal tissues. To determine whether this addressin is a specific adhesion molecule for lymphocytes, we have isolated it by monoclonal antibody-affinity chromatography and inserted it into supported phospholipid planar membranes. Lymphocytes bind to membranes containing the addressin, but not to phospholipid bilayers or to control glycophorin-reconstituted membranes. Only those lymphocytes and lymphoma cell lines capable of binding to mucosal HEV adhere well to the isolated addressin; peripheral lymph node HEV-specific or HEV-non-binding cell lines do not bind. Binding is blocked by anti-addressin antibody MECA-367. We conclude that the mucosal vascular addressin is a tissue-specific endothelial cell-adhesion molecule for lymphocytes, and suggest that it could regulate lymphocyte traffic into mucosal tissues by mediating attachment of blood-borne cells to endothelium.     

调和共轭点偶或线偶纯综合射影定义

给出调和共轭点(线)偶纯综合射影定义，并证明射影定义与代数定义的等价性。     

量子系综对的量子关联性

研究一对量子系综{ε,η}的量子关联性。在量子信息论中,通过量子测量只能知道量子系统的状态ρ以一定的概率pi处于某个状态ρi,从而得到一系列的量子态ρ1,ρ2,…,ρn以及它们出现的相应概率p1,p2,…,pn;进而得到一个"量子系综"ε={pi,ρi}ni=1。构造一个四体量子态ρε,η,利用量子相对熵,定义了反映"量子系综对"所含量子关联的度量函数,揭示了这个度量函数的一些性质。