共查询到20条相似文献,搜索用时 0 毫秒
1.
2.
Summary Hypothalamic tyrosine hydroxylase (TH) activity of castrate rats is modulated by testosterone propionate (TP) in vivo. Kinetic studies revealed that bothV
max andK
m were virtually unaltered for substrate tyrosine in the presence of an excess of DMPH4 cofactor. TP replacement to castrate rats increased theK
m for added DMPH4 cofactor, whileV
max decreased. These results suggest that TP decreases TH activity of castrate rats by inhibiting the enzymereduced pteridine cofactor complex. 相似文献
3.
Hypothalamic tyrosine hydroxylase (TH) activity of castrate rats is modulated by testosterone propionate (TP) in vivo. Kinetic studies revealed that both Vmax and Km were virtually unaltered for substrate tyrosine in the presence of an excess of DMPH4 cofactor. TP replacement to castrate rats increased the Km for added DMPH4 cofactor, while Vmax decreased. These results suggest that TP decreases TH activity of castrate rats by inhibiting the enzyme-reduced pteridine cofactor complex. 相似文献
4.
5.
Riassunto Nel muscolo bulbocavernoso dorsale (elevatore dell'ano) di ratto per effetto della castrazione, e rispettivamente della susseguente somministrazione di testosterone, si producono notevoli modificazioni, in senso inverso, in strutture contenenti RNA e che sono importanti per la sintesi proteica (nucleoli e ribosomi citoplasmatici).
Supported by Muscular Dystrophy Associations of America Inc. and Consiglio Nazionale delle Ricerche, Roma, Italy. 相似文献
Supported by Muscular Dystrophy Associations of America Inc. and Consiglio Nazionale delle Ricerche, Roma, Italy. 相似文献
6.
7.
P Corbier R Picon J Roffi 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1977,285(14):1247-1249
The changes in serum testosterone and dihydrotestosterone concentrations have been measured in the newborn Rat, before, during and up to 6 hrs after birth. A sudden and transient increase of serum testosterone has been found between 0 and 2 hrs. At 4 hrs, the value returns to that found in the foetus at the end of gestation. 相似文献
8.
9.
10.
C. Valenti María I. Vacas D. P. Cardinali 《Cellular and molecular life sciences : CMLS》1979,35(1):120-122
Summary Tubulin levels of the medial basal hypothalamus (MBH) were greater in male than in female rats. Orchidectomy brought about a decrease of MBH tubulin concentration, whereas testosterone injection augmented it in the MBH and adenohypophysis. Estradiol administration augmented MBH tubulin and protein concentration.This study was supported in part by grants from the Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina (CONICET) (grant No. 6638), and the Programa Latinoamericano de Investigación en Reproducción Humana (PLAMIRH 2.3.1.75 R). 相似文献
11.
Zusammenfassung Die Noradrenalinkonzentration im Vas deferens und den Vesiculae seminales erhöht sich nach Kastration, wird aber nach Behandlung mit Testosteron leicht vermindert. Der gesamte Noradrenalingehalt erfährt jedoch nach keiner der beiden Behandlungen eine bedeutende Veränderung verglichen mit unbehandelten Kontrollorganen. Das bedeutet, dass Androgene keinen ausgesprochenen Einfluss auf die adrenergische Innervation per se haben, sondern hauptsächlich Gewebe, wie Glattmuskel- und sekretorische Zellen, influieren. 相似文献
12.
The pineal gland of the male rat does not appear to rely on prior conversion of testosterone to estradiol for the stimulant effect of testosterone on pineal melatonin and 5-methoxytryptophol synthesis. 相似文献
13.
Summary The pineal gland of the male rat does not appear to rely on prior conversion of testosterone to estradiol for the stimulant effect of testosterone on pineal melatonin and 5-methoxytryptophol synthesis. 相似文献
14.
J. A. Moguilevsky C. Libertun Berta Szwarcfarb 《Cellular and molecular life sciences : CMLS》1969,25(4):378-379
Resumen En el presente trabajo se ha estudiado la actividad de la citocromooxidasa en diversas areas hipotalamicas de animales machos castrados y con terapia sustitutiva. Los resultados demonstraron que la castración deprime la actividad de la enzima en el hipotálamo anterior y posterior. La posible implicancia de estos hallazgos con cambios en la cadena respiratoria producidos por la castration es discutida en el trabajo.
Supported by Consejo Nacional de Investigaciones Científicas y Técnicas. 相似文献
Supported by Consejo Nacional de Investigaciones Científicas y Técnicas. 相似文献
15.
16.
17.
Tubulin levels of the medial basal hypothalamus (MBH) were greater in male than in female rats. Orchidectomy brought about a decrease of MBH tubulin concentration, whereas testosterone injection augmented it in the MBH and adenohypophysis. Estradiol administration augmented MBH tubulin and protein concentration. 相似文献
18.
19.