共查询到20条相似文献,搜索用时 31 毫秒
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A yeast activity can substitute for the HeLa cell TATA box factor 总被引:55,自引:0,他引:55
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Reversion of a promoter deletion in yeast 总被引:24,自引:0,他引:24
Promoter function in yeast has been examined by obtaining revertants of a his3 promoter deletion in vivo. Events which provide a new promoter for the his3 gene include insertion of the transposable element Ty1, rearrangements of the plasmid vector, and chromosomal mutations. A role for dicentric chromosomes as a source of the plasmid rearrangements is discussed. 相似文献
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Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box 总被引:75,自引:0,他引:75
The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors. 相似文献
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分别基于Markov链模型、频率分析和加权Markov链模型分析k-mer(主要考虑k=6的情形)在DNA序列中的使用情况,并以此定义模糊相对熵度量2个DNA序列结构的差异程度.将转录频率较低的启动子序列作为对照,分析其它转录频率不同的酵母基因启动子序列与对照序列中k-mer隶属度的模糊相对熵的变化,发现基因转录频率与模糊相对熵存在线性正相关关系.一般地,转录频率相差越大的基因,其启动子序列结构的差异越明显.这提示酵母基因启动子序列结构与基因转录频率有一定关联性.与Markov链模型和频率分析法比较,加权Markov链模型的模糊相对熵能更有效地度量基因启动子序列结构的差异. 相似文献
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Heat shock factor is regulated differently in yeast and HeLa cells 总被引:27,自引:0,他引:27
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Bent DNA at a yeast autonomously replicating sequence 总被引:52,自引:0,他引:52
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Global histone acetylation and deacetylation in yeast 总被引:67,自引:0,他引:67