Filamentous bodies in human glomerulonephritis

Summary Filamentous bodies have been identified in the glomerular cells of human kidney biopsies. These structures have a close morphological resemblance to ciliary rootlets, although the cells of the glomerular tuft only occasionally bear cilia. Their significance could be, as for cilia, of a cellular disdifferentiation of a pathological cellular proliferation.     

Filamentous structures in normal taste bud

Riassunto Nella presente nota sono analizzate e brevemente discusse le caratteristiche submicroscopiche e distributive delle strutture filamentose presenti nei principali tipi cellulari del calice gustativo.     

Filamentous growth of someMycoplasma species of man

Zusammenfassung M. hominis und M.orale 1 bildeten in flüssigen Medien Filamente von unterschiedlicher Länge. Daneben konnten auch stern- und rosettenähnliche Formen sowie Diploformen beobachtet werden.M. salivarium, M. fermentans undM. orale 2 zeigten nur Diploformen.     

Detection of fibrillary bodies in human and experimental leukemias by polarizing microscopy]

An optical polarizing microscope with a good coefficient of extinction permits the visualization of the cytoplasmic fibrillar body in living preparations and smears of leukemic cells (human leukemias and the L 5222 experimental leukemia). These inclusions are not visible by phase contrast microscopy nor in fixed and stained smears.     

Mendelian recessive ratios in acute poststreptococcal glomerulonephritis

Summary A prospective study of 15 families (61 siblings) of index cases of acute poststreptococcal glomerulonephritis detected a proportion of 0.260±0.016 SEM. This is an excellent fit for a single autosomal recessive trait.This study was supported by CONICIT grants SAL-S1-001 and 3126-S1-0663 (Venezuela) and Grants in Aid from CONDES (Universidad del Zulia) and Asociacion de Amigos del Riñón (Maracaibo).     

Immune-mediated glomerulonephritis induced by mercuric chloride in mice

Summary The BALB/c mouse developed mesangial deposits of immune constituents and light microscopical changes characteristic of immune complex glomerulonephritis after 8 weeks' treatment with mercuric chloride given by s.c. injection. There were no signs of linear of granular immune deposits along the glomerular capillary basement membrane after 2 or 8 weeks. The antigen could not be identified. No antibodies to nuclear or renal structures were found. Using a histochemical method (silver amplification) mercury was detected by light and electron microscopy in tubular and glomerular structures. Mercury was present in secondary lysosomes of the mesangial cells after eight weeks of mercury poisoning.We are deeply indebted to Dr. Gorm Danscher, Institute of Anatomy, B., University of Aarhus, Denmark, for valuable discussions and technical advice. This work was supported by the Swedish Medical Research Council, project no 6536.     

Nuclear multivesicular bodies in cultured hamster cells

Zusammenfassung Mit elektronenmikroskopischer Untersuchung von BHK 21 cl 13 Zellen wurden multivesikuläre Körperchen im Karyoplasma festgestellt, Strukturen, die direkt der inneren Kernmembran entstammen. Die multivesikulären Körperchen wie auch die internen vesikulären Elemente ( 90 nm) waren von einer einzigen Membran umgeben.

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Acknowlegdment: we thank Miss.P. Martinez Venteo for her excellent technical assistance.     

Hydrogen peroxide and Heinz bodies

Zusammenfassung In den mit Cyanid vergifteten Erythrozyten produziert das exogene H₂O₂ bei geeigneter Temperatur Heinzsche Körperchen. Die Bildung der Heinzschen Körperchen, ihre Anzahl und Grösse ist von Temperatur und Cyanid-Konzentration abhängig.     

Spinoza on the resistance of bodies

Commentators often claim that the bodies of Spinoza’s physics resist the changes they undergo. But it’s not always clear what they mean when they say this, or whether they are entitled to say it. This article clarifies what it might mean to for Spinoza’s bodies to resist change, and examines the evidence for such a view. In the first half, the author argues that there is some limited evidence for such a view, but not nearly as much as people think. In the second half, the author proposes looking for a mental analogue to collision in the realm of ideas and argues that adequacy amounts to a meaningful concept of resistance in Spinoza, albeit one that is incomplete.