我院住院癌痛患者麻醉药品药物利用调查分析

为临床癌痛患者麻醉药品的合理使用和科学管理提供参考,回顾分析我院2007年1—6月份用于癌痛治疗的麻醉药品处方,以用药频度和药物利用指数作为判断合理用药的标准,分析各药的使用情况。在3390份处方中(男性患者多于女性,肿瘤分布中肺癌排名第一),美施康定(30mg)的DDDs最高(DDDs=1384.30),各药的DUI≤1.0。说明我院住院癌痛患者麻醉药品的使用基本合理,部分临床医师的用药习惯还有待改进,建议进一步加强癌症三阶梯止痛指导原则的宣传。     

贝那普利与缬沙坦联合应用对原发性高血压的心脏保护作用

目的:观察抗高血压药贝那普利与缬沙坦联合应用对原发性高血压的心脏保护作用。方法:对原发性高血压左心室肥厚患者109例,采用缬沙坦联合贝那普利治疗,疗程6个月。用药前后测定高敏C反应蛋白与左心室厚度。结果:与治疗前比较,高敏C反应蛋白(hsCRP)下降,收缩压与舒张压明显下降,舒张末期左室后壁厚度(LVPWD)、舒张末期室间隔厚度(IVST);较治疗前显著下降,差异有统计学意义。结论:对原发性高血压病人,有协同作用的降压药联合应用,能降低高血压的血管炎症作用,同时逆转左心室肥厚,对心脏有保护作用。     

美托洛尔联合非洛地平治疗高血压的临床观察

观察美托洛尔联合非洛地平治疗高血压的临床疗效;分为治疗组与对照组,治疗组为口服美托洛尔和非洛地平,对照组为口服美托洛尔;60例治疗组和40例对照组治疗过程中未发现严重的副作用,治疗组与对照组的治疗效果有显著差异(P0.05);美托洛尔联合非洛地平治疗高血压效果比单一的美托洛尔好。     

比索洛尔长期治疗老年高血压疗效及不良反应分析

讨论比索洛尔长期治疗老年高血压疗效及不良反应分析。选取60例陇西县第一人民医院在2016年12月到2018年12月治疗的老年高血压患者,根据患者入院时间顺序分为实验组(比索洛尔长期治疗)和对照组(常规降压药治疗)。在收缩压以及舒张压的情况上,实验组小于对照组,比较差别较大(P0.05)。在不良反应发生率以及停药率上,实验组小于对照组,比较差别较大(P0.05)。在实验组中根据给药剂量的增加,不良反应发生率以及停药率也在发生变化。在老年高血压患者的治疗中使用比索洛尔长期治疗,能够有效的控制血压,减少不良反应发生率,随着用药剂量的增加,不良反应发生率以及停药率也会增加,在治疗中需要严格控制用药剂量,具有重要的临床价值。     

卡托普利联合厄贝沙坦治疗肾实质性高血压患者的临床疗效

目的比较肾实质性高血压患者应用卡托普利和厄贝沙坦的疗效,并研究两者联合用药的疗效情况。方法选取2017年1月～2018年12月在丹阳市第三人民医院住院并被确诊为肾实质高血压的患者160例,随机分成厄贝沙坦治疗组(A组)、卡托普利治疗组(B组)、厄贝沙坦+卡托普利减半剂量联合治疗组(C组)、厄贝沙坦+卡托普利同等剂量联合治疗组(D组)。治疗12周后对比四组患者的血压、24 h尿蛋白、血肌酐和尿β_2-微球蛋白以及不良反应的发生情况。结果四组患者的收缩压、舒张压以及24 h尿蛋白、血肌酐和尿β_2-微球蛋白在治疗后都有明显改善(P0.05),联合治疗组均比单药治疗组对血压和肾功能的改善作用更显著。对比四组不良反应发生情况,卡托普利和厄贝沙坦同等剂量联合组的不良反应发生率明显高于其他三组。结论卡托普利联合厄贝沙坦治疗肾实质性高血压的效果较单药治疗更好,且两种药物减半剂量联用的安全性更好。     

女性高血压治疗的进展

<正> 高血压是常见的心血管疾病。老年人中的高血压发病率高,而女性寿命长于男性,美国的女性高血压患者多于男性。我国的高血压患者99％是原发性高血压。妊娠和服用避孕药物是仅存在于女性的高血压病诱发因素。雌激素补充治疗对血压也有影响,本文     

贝那普利联合美托洛尔治疗老年原发性高血压合并心力衰竭的临床研究

研究分析贝那普利与美托洛尔联合治疗老年原发性高血压伴有心力衰竭的临床效果。择取2013年1月-2015年2月期间在兰州市中医医院应用药物治疗的72例原发性高血压伴有心力衰竭的老年患者,通过计算机数字表法进行分组,对照组36例患者单纯使用贝那普利进行治疗;治疗组36例患者在贝那普利用药的同时加用美托洛尔进行治疗。治疗组患者的左心室射血分数、左心室舒张末期内径、左心室收缩末期内径等指标均显著优于对照组,差异P0.05有统计学意义。治疗组患者的心率、舒张压以及收缩压水平显著低于对照组,差异P0.05有统计学意义。贝那普利与美托洛尔联合治疗老年原发性高血压伴有心力衰竭的降压效果甚是理想,协同作用良好,能明显改善老年患者的心功能,避免或减缓病情的发展。     

临床药师干预对促进高血压患者合理用药的效果分析

分析临床药师干预对促进高血压患者合理用药的效果。选取2015年9月~2017年2月甘肃省定西市安定区第二人民医院接收的高血压患者148例,并随机将其划分为观察组与对照组,每组均74例。对照组仅给予常规干预,观察组在对照组基础上实施临床药师干预。比较2组患者不合理用药情况及血压控制情况。观察组药物选择不合理、重复用药、用法不合理、用药剂量不合理及联合用药不合理等情况发生率6.76%较对照组的18.92%低(P0.05);观察组干预后收缩压及舒张压均较对照组低(P0.05)。高血压患者实施临床药师干预,可明显减少不合理用药发生情况,有效调节血压水平。     

浅谈老年高血压患者的家庭用药指导

正确、安全、联合使用降压药可以让老年高血压患者的高血压得到有效控制。为此,本文在查阅相关资料的基础上,对社区老年高血压患者的家庭用药需要掌握的特点和注意事项进行阐述,旨在提高他们对高血压用药的重要性的认识,加强服药的依从性,尽可能做到安全用药,有效地控制血压,避免因高血压而导致一系列的并发症的发生。     

硝酸甘油气雾剂治疗高血压急诊的临床观察

1　对象与方法1.1　对象 :原发性高血压患者 46例 ,男性 32例 ,女性 14例 ,年龄 39～ 72岁 (平均 6 1.5岁 ) ,高血压病程 3～ 2 7年 (平均 15 .7年 )。其舒张压均在 115ｍｍＨｇ( 1ｍｍＨｇ =0 .133ｋｐａ)以上 ,最高收缩压为 2 2 0ｍｍＨｇ ,最高舒张压为 14 0ｍｍＨｇ ,青光眼等患者本药禁忌症除外。1.2　治疗方法 :取同一手臂和体位测基础血压及用药后 15分钟测血压各一次 ,再测用药后 30及 45分钟血压。硝酸甘油气雾剂喷于舌下 3～ 5揿 /次 ,每揿含药 0 .5ｍｇ。1.3　观察指标及方法 :由固定医师负责测定血压 ,使用立式水银柱血压计。按…     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

An Analysis of Catherine＇s Character——Wuthering Heights

Wuthering Heights, Emily Bronte＇s only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

Achieving Unusual States of Matter Under High Pressure

正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Density Functional Theory for the Response of Periodic Systems to Electric Fields Based on the Vector Potential Approach

正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that     

Call for Papers

<正>"The Journal of Shanghai Normal University:Mathematics"is published by Shanghai Normal University as regular issues of The Journal of Shanghai Normal University each year from 2014 in English.The editors-in-chief of the issues are professors Yuhao Cong and Maoan Han.The Journal of Shanghai Normal University was started in 1958 with