Ein chemisch neuartiger Vasodilatator mit Wirkung auf die Lungenstrombahn

Summary 4-[5-Amino-3-(4-pyridyl)-1 pyrazolyl]-1-methyl-piperidine (CIBA 31531-Ba) was found to have a relatively pronounced vasodilator effect on the pulmonary circulation in the open chest, right heart-bypass cat with fixed cardiac output. This compound most probably has a direct effect on the vascular smooth muscle.     

Ein neuer Weg zur Gewinnung von Zellen- und Gewebebestandteilen

Summary A new method to obtain cells and tissue ingredients almost unalterated is described. The tissue is emulsified in an indifferent oil in which process the different histological structures are separated into the different droplets. Separating similar droplets, it is possible to gain single cells and tissue components.     

Über den Einfluss von Natriumsulfit,Natriumtellurit und Natriumselenit auf die Retention von Zink,Kadmium und Quecksilber im Organismus

Summary The influence of sodium sulfite, sodium tellurite and sodium selenite on the retention of zinc, cadmium and mercury in mice was studied. The retention of mercury was increased by sodium selenite and by sodium tellurite. The retention of cadmium was increased only by sodium selenite. Sodium sulfite did not influence the retention of metals studied. The retention of zinc was not influenced by any compounds used.     

Die Wirkung von synthetischem Oxytocin (Syntocinon) und Acetazolamid auf die Ausscheidung von Wasser,Natrium und Kalium

Summary Changes in water, sodium, and potassium excretion following administration of synthetic oxytocin (Syntocinon)—alone or in combination with acetazolamide— resemble the changes that occur after an equivalent dose of neurohypophysial extract containing oxytocin. Since the action of Syntocinon on water and sodium excretion is manifest when carbonic anhydrase in kidney tissue is fully inhibited by acetazolamide, it may be assumed that the mechanism whereby Syntocinon increases sodium excretion is independent of carbonic anhydrase. Oxytocin does not affect ultrafiltration in the glomeruli (Krause ⁴) and would therefore appear to modify the reabsorption or excretion process in the tubuli.     

Der Briefwechsel von E. S. von Fedorow und F. Klein, 1893

Ohne Zusammenfassung B. L. van der Waerden zum 70. Geburtstag gewidmet Vorgelegt von B. L. van der Waerden     

Der Briefwechsel von E. S. von Fedorow und A. Schoenflies, 1889–1908

Ohne Zusammenfassung Vorgelegt von B. L. van der Waerden Herrn Professor I. I. Schafranovsky, Berginstitut Leningrad, in Dankbarkeit gewidmet     

Elektrischer Widerstand,Aussendurchmesser der Spitze und Wandstärke von Glas-Mikroelektroden

Summary Electrical impedance and outside tip diameter of glass microelectrodes were measured. With outside tip diameters smaller than 0.7 there was a significant deviation between calculated and measured values. The relationship between outside tip diameter and wall thickness was investigated electronmicroscopically on micropipettes filled with phosphotungstic acid.

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Mit Unterstützung des Schweizerischen Nationalfonds, Projekt Nr. 2903.     

Der Einfluss von Acetylcholin auf die42Kalium-Abgabe postnataler,denervierter und reinnervierter Skeletmuskulatur

Summary The loss of⁴²K from the isolated rat diaphragm into the bathing solution is increased by acetylcholine, (a) 3 to 4 days after birth, (b) 7 to 14 days after sectioning of the phrenic nerve. The⁴²K loss is not altered by acetylcholine in the diaphragm of adult rats and after the denervated diaphragm has become reinnervated.     

Wirkung von NIH-LH auf das Ovar unreifer Ratten unter Progesteron-, Norgestrel- und Lynestrenol-Einfluss

Summary The influence of NIH-LH upon the ovary of infantile rats can be eliminated by treatment with progesterone, norgestrel and lynestrenol. This result suggests suppression of the hypophysary functions of gonadotropines. A direct influence of lynestrenol on the ovary suggests the presumption that some tertiary follicles change haemorrhagically.

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Die Untersuchungen wurden mit einer Forschungsbeihilfe der Ford Foundation durchgeführt.     

Die Wirkung von Benzpyren,Zigarettenrauchkondensat und passiver Berauchung auf die Bildung der Zoxazolaminhydroxylase

Summary Treatment with Benzo(a) pyrene, cigarette smoke condensate and cigarette smoke on hamsters and rats is able to induce zoxazolaminhydroxylase. Enzyme activity in hamsters is a priori higher, whereas the enzyme system in rats is of higher inducibility.     

Einfluss von augenstielextrakt auf trehalose,fructose und glucose in der hämolymphe vonOrconectes limosus

Summary Quantitative changes of glucose, fructose and trehalose in the hemolymph ofOrconectes limosus were measured after injection of eyestalk extracts. Especially in February and March high levels of trehalose were found after hormone injection.     

Untersuchungen über die Wirkung von Kinetin auf Kallus und Tumoren bei Organkulturen vonNicotiana glauca,N. langsdorffii und deren amphidiploiden Bastard

Summary In leaf cultures ofNicotiana glauca, N. langsdorffii, and their amphidiploid hybrid, callus growth or tumor formation is enhanced by kinetin, depending on its concentration. Of the 2 species and their hybrid, maximum response was found in the hybrid, less inN. glauca, the slightest response being found inN. langsdorffii. These facts confirm the earlier finding of a connection between callus-forming potency inN. glauca and tumor formation in its hybrid.

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Den Herren Prof. Dr.G. de Lattin (Zoologisches Institut der Universität des Saarlandes) und Prof. Dr.F. Anders (Genetisches Institut der Justus Liebig-Universität, Giessen) bin ich für die Förderung dieser Arbeit zu grösstem Dank verpflichtet.     

Einbau von H3-thymidin in zellen und gewebe vonHelix pomatia L. (gastropoda,pulmonata)

Summary It has been demonstrated by injections of H³-Thymidine into adult and juvenile snails (Helix pomatia) that the mitotic activity in the central nervous system, the connective tissue and epidermis was generally higher in juvenile animals than in adult ones. Data are given for the amount of triated thymidine labelled nuclei in the tissues, which are investigated.     

Untersuchungen zur Klärung der Funktion des Reissnerschen Fadens. In-vitro-Bindung von Noradrenalin,Adrenalin und Serotonin

Summary The glycoprotein of Reissner's fibre is able to bind norepinephrine, epinephrine and serotonin. Bound amines can be demonstrated at the RF, even after washing with artificial cerebrospinal fluid for some, hours. It is discussed whether it is a function of the RF to remove substances, for instance biogenic amines, from the cerebrospinal fluid.     

Über die Wirkung von Diäthyläther auf die Aktivität der Glykogenphosphorylase und Phosphorylaseb-Kinase in Herz,Skeletmuskel und Leber der Ratte

Summary The rise of phosphorylasea activity and the activation of phosphorylaseb kinase in skeletal muscle of the rat in diethyl ether anaesthesia are inhibited by a blocker of the adrenergic receptors, pronethalol. This agent has no effect on the increased activity of liver phosphorylase under the same conditions. There are no effects of this anaesthetic on the phosphorylasea level in myocardium.     

Über die Entstehung von Dehydracetsäure und ihren Analogen bei der Oxydation derα, γ, δ, ζ-Tetraketone mit Bleitetraacetat

Summary Oxidation of, , , -Tetraketones (I) with lead-tetraacetate yields dehydracetic acid and analogous compounds (IV). The reaction can be understood if one assumes that acylketenes (III) are formed as intermediates through the glycol-fission of the dienolic form II of the tetraketones.     

Die Veränderung des Stärke-, Protein- und RNS-Gehaltes vonLemna minor L. unter dem Einfluss von Kinetin (6-Furfurylaminopurin)

Summary Kinetin (6-furfurylaminopurine) is rapidly absorbed byLemna minor L. 3 · 10^–8 M/ml medium cause an immediate but temporary stimulation of RNA and protein synthesis during the first hour of the treatment. The following excessive accumulation of starch is considered to be more or less a direct consequence of a disturbed RNA and protein metabolism.