Regulation of canonical Wnt/β-catenin pathway in the nucleus

Canonical Wnt/β-catenin pathway plays a central role in development, homeostasis, as well as tumorigenesis. The regulation of the pathway involves various and complicated mechanisms, including the extracellular, intracellular and endonuclear regulation. As the key component of the pathway, the Lefl/Tcfs-β-catenin complex is also the key target of regulation in the nucleus. In the current review, we are going to summarize the regulators in the nucleus which can modify the transcrip- tional activity of the Wnt/β-catenin pathway.     

放大器的线性失真和非线性失真

分析了失真产生的原因，又通过具体电路的具体波形分析了线笥失真和非线性失真的区别与系；最后又根据分析情况介绍了减少线性失真和非线性失真的方法步骤。     

文艺复兴时期欧洲声乐艺术的特点与成就

"文艺复兴"是西方文明史上的一次重大的思想文化运动。文艺复兴时期音乐文化的重要特点,一是世俗音乐的发展,二是专业音乐的发展。声乐艺术在文艺复兴时期所取得的成就及在各个历史时期的发展、变革以及各种流派和风格的产生,必然和当时社会的现状紧密相连。     

在OPENSSL中自定义加密卡中的SCB算法

在使用OpenSSL来进行加解密时,会使用一些自定义的特殊算法,如:加密卡设备中的SCB算法.本文介绍自定义Engine(引擎)机制,这种机制运行OpenSSL使用第三方提供的硬件加密设备进行数据加解密运算;在Evp中自定义SCB对称加密算法封装函数,有点类似PKCS#11 提供的接口标准.结果表明,大量的信息在网络中传输时,更能保证用户间通信的安全与保密性,以此符合国家对加解密算法的标准.     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.     

气体对阴离子表活剂压裂液破胶实验研究

阴离子表活剂压裂液是新型清洁压裂液,原油和地层水对其破胶机理与实验研究已相当充分,但气体对其破胶作用至今研究很少.为解决阴离子表活剂压裂液在压裂应用中的障碍,研究采用一套实用的实验流程,评价了天然气、氮气、二氧化碳三种常见气体对阴离子表活剂压裂液的影响.实验证明,三种不同的气体对阴离子表活剂压裂液的降粘幅度存在较大的差别,其中,二氧化碳气体对阴离子清洁压裂液降粘幅度最大,可使交联液体彻底破胶,天然气对阴离子型表活剂压裂液降粘幅度较小,氮气对阴离子压裂液的粘度几乎没有影响,氮气和天然气可以使液体泡沫化,从而有利于返排.实验结果为优化压裂设计提供了依据,可有效提高现场压裂施工成功率.     

试验机稳定加载条件的修正及伺服控制的本质

本文通过对试验机-试样系统的分析,认为试验的稳定加载条件不仅仅取决于试验机和试样的刚度(K_m+K_r),而且取决于试验机活塞(端部)的位移速率.具有反馈系统的伺服试验机,正是通过对活塞位移U_q的控制来谐调刚度(K_m+K_r)的变化,从而达到控制应变速率,以保证加载过程的稳定.     

多腔速调管主要性能指标简化分析

介绍了速调管在我国的发展现状和几种不同结构的多腔速调管的主要特性比较,并给出了小信号条件下速调管的各种主要特性的简化分析方法.在这种简化分析方法中,把多腔速调管看作是几个双腔速调管的级联,并且没有考虑非线性、空间电荷效应和相对论效应等带来的影响,目的是阐述基本原理和基本分析方法.     

Exchange-Correlation and Electronic Excitation Energies from Pairing Matrix Fluctuations

We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.