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1.
随着医药卫生事业的发展,萜类化合物与环糊精的包合物的研究成为超分子化学的研究热点.综述了具有较高生物活性的萜类化合物(如青蒿素、紫杉醇、丹参酮、穿心莲内酯、印楝素和齐墩果酸等)与环糊精的包合物的研究进展.  相似文献   

2.
基于文献检索,概述了近年来中国柳珊瑚中萜类化合物的化学成分和生物活性研究进展,从中发现了一些结构独特并具有强生物活性的萜类化合物,尤其是Briarane型二萜显示潜在的药用价值。  相似文献   

3.
对黄花蒿植物凝血物质基础进行了探究.采用有机溶剂提取法对黄花蒿植物进行浸提;采用凝血板法、试管法、血浆复钙时间测定法检测浸提物凝血药效;采用碱溶酸沉淀法及低温法对正丁醇浸提物的黄酮类化合物、萜类化合物进行分离并分析了黄酮类化合物紫外可见光谱及荧光光谱性质;采用理化显色反应对化合物进行鉴定,并利用TLC显色反应对萜类化合物进行分析.结果表明:黄花蒿植物凝血药效部位为正丁醇浸提物,正丁醇浸提物在不同的检测方法中均有显著的凝血药效,正丁醇浸提物主要化学组分为黄酮类化合物及萜类化合物.说明黄花蒿植物凝血药效部位为正丁醇浸提物,其化学组分主要为黄酮类化合物及萜类化合物.  相似文献   

4.
海鞘中抗肿瘤活性物质的研究   总被引:1,自引:0,他引:1  
描述了海鞘的生态特征,并按肽类、生物碱类、聚醚类、大环内酯类、萜类化合物类、多硫化物类等化学结构分类.介绍了国内外对海鞘抗肿瘤活性成分的研究。显示了诱人的研究开发前景,为开发和利用海鞘资源奠定了基础。  相似文献   

5.
萜类化合物是药用植物中结构和生物活性多样化的一类大分子化合物,是自然界中广泛存在的次级代谢产物,主要应用于食品、保健品、医药等领域。生物信息学和分子生物学研究的不断深入,极大促进了药用植物四环三萜皂苷的生物合成途径解析与关键功能基因的挖掘鉴定。本文对常见药用植物四环三萜皂苷的生物合成学研究现状展开论述,重点介绍以药用植物四环三萜皂苷为代表的几类化合物的分子合成机制和生物合成研究进展,为人工构建、优化微生物“细胞工厂”,高效合成稀有、高附加值的四环三萜类化合物,推动药用植物资源可持续利用等提供参考。  相似文献   

6.
萜类是一类具有重要研究及药用价值的天然化合物.近年来,随着萜类合成途径中各种关键酶基因克隆、异源表达和功能鉴定,许多萜类生物合成途径逐渐清晰.以萜类微生物生物合成过程中的中间产物为线索,综述了应用代谢工程、合成生物学、系统生物学等技术开展的萜类微生物生物合成的研究进展.  相似文献   

7.
据C8LEN周刊网站2012年11月26日报道,科学家发现了一种新型萜烯合成酶,有助于人们理解植物究竟如何合成不同寻常的环烯醚萜类化合物(iridoids)的。  相似文献   

8.
八种蒿属植物石油醚提取物中萜类成分分析   总被引:3,自引:0,他引:3  
以气相色谱-质谱计算机联用分析了蒙古蒿、矮蒿、毛莲蒿(蒿亚属)以及牛尾蒿无毛变种、牛尾蒿原变种、猪毛蒿、南牡蒿及华北米蒿(龙蒿亚属)石油醚提取物中的萜类成分,共鉴定出123种萜类化合物,其中单萜57种,倍半萜66种。从萜类化合物结构来看,这八种蒿属植物石油醚提取物中,双环萜(单萜,倍半萜)结构类型比较相似。三种蒿亚属植物的石油醚提取物中含有多种链状单萜,而三环萜类(倍半萜)仅有5种类型;五种龙蒿亚属植物的石油醚提取物中链状单萜类型单调,而三环萜类(主要是倍半萜)达11种类型之多。这在一定程度上反映出龙蒿亚属植物化学系统比蒿属植物化学系统进化  相似文献   

9.
植物精油及萜类成分的生物活性   总被引:17,自引:0,他引:17  
论述了植物精油及其中所含的萜类化合物对生物的生命活动的重要作用。对植物精油在抗菌,杀菌,诱虫,驱虫,杀虫,杀卵和影响植物生长等方面的研究进展进行了介绍。  相似文献   

10.
从苦楝籽中提取多萜类化合物的研究   总被引:7,自引:0,他引:7  
用多种溶剂浸渍苦楝籽作对比实验 ,结果表明 ,用 2 0 %的甲醇水溶液 ,在 6 0℃时浸渍提取多萜类化合物的收效较好 ,产率较高 .  相似文献   

11.
Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.  相似文献   

12.
何延凌 《科技信息》2008,(4):258-258
Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women's language from these perspectives: pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women's language, more attention should be paid to language use in social context. What's more, the linguistic phenomena in a speaking community can be understood more thoroughly.  相似文献   

13.
王慧 《科技信息》2008,(10):240-240
Wuthering Heights, Emily Bronte's only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.  相似文献   

14.
The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.  相似文献   

15.
理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。  相似文献   

16.
As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.  相似文献   

17.
正The periodicity of the elements and the non-reactivity of the inner-shell electrons are two related principles of chemistry,rooted in the atomic shell structure.Within compounds,Group I elements,for example,invariably assume the+1 oxidation state,and their chemical properties differ completely from those of the p-block elements.These general rules govern our understanding of chemical structures and reactions.Using first principles calcula-  相似文献   

18.
We have developed an adiabatic connection to formulate the ground-state exchange-correlation energy in terms of pairing matrix linear fluctuations.This formulation of the exchange-correlation energy opens a new channel for density functional approximations based on the many-body perturbation theory.We illustrate the potential of such approaches with an approximation based on the particle-particle Random Phase Approximation(pp-RPA).This re-  相似文献   

19.
正The electronic and nuclear(structural/vibrational)response of 1D-3D nanoscale systems to electric fields gives rise to a host of optical,mechanical,spectral,etc.properties that are of high theoretical and applied interest.Due to the computational difficulty of treating such large systems it is convenient to model them as infinite and periodic(at least,in first approximation).The fundamental theoretical/computational problem in doing so is that  相似文献   

20.
For molecular systems,the quantum-mechanical treatment of their responses to static electromagnetic fields usually employs a scalar-potential treatment of the electric field and a vector-potential treatment of the magnetic field.Although the potential for each field separately is associated with the choice of an(unphysical)origin,the precise choice of the origin for the electrostatic field has little consequences for the results.This is different for the  相似文献   

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