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| 单操作者大鼠腹腔异位心脏移植模型的建立与改良 | |
| 引用本文： | 曾顺,刘达兴. 单操作者大鼠腹腔异位心脏移植模型的建立与改良[J]. 实验动物科学, 2021, 38(3): 70-74 |
| 作者姓名： | 曾顺 刘达兴 |
| 摘 要： | 目的 学习并改良大鼠腹腔异位心脏移植模型的建立过程,降低手术难度,减短学习周期,使模型易建立以供于移植免疫、病理、药理等方面的研究.方法 建立大鼠腹部异位心脏移植模型,归纳总结整个过程中的操作技巧.结果 正式实验30例,存活29例,存活率96.7％.术中刺伤心脏,开放后无法止血死亡1例,供心阻断时间为(24.2±5.0... |
| 关 键 词： | 心脏移植 单操作者 异位移植 动物模型 |
Establishment and Improvement of Abdominal Heterotopic Heart Transplantation Model in Rats by Single Operator |
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| ZENG Shun,LIU Daxing. Establishment and Improvement of Abdominal Heterotopic Heart Transplantation Model in Rats by Single Operator[J]. Laboratory Animal Science, 2021, 38(3): 70-74 | |
| Authors: | ZENG Shun LIU Daxing |
| Abstract: | Abstract: Objective To study and improve the establishment process of rat abdominal heterotopic hearttransplantation model, reduce the difficulty of operation, shorten the learning cycle, and make the model easy toestablish for the study of transplantation immunity, pathology and pharmacology. Method Through theestablishment of rat abdominal heterotopic heart transplantation model, the operation skills were summarized in thewhole process. Result There were 30 cases in the formal experiment, and the survival rate was 96. 7%. One casedied of stabbing the heart during the operation and failed to stop bleeding after opening. The average cold ischemiatime was ( 24. 2 ± 5. 0) minutes and total operation time was ( 59. 8 ± 0. 0) minutes. Conclusion The modifiedoperation method of rat abdominal heterotopic heart transplantation model can shorten the operation time, reduce the difficulty of operation, and improves the sucess rate of the operation. |
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