Immuno-electron microscopic localization of fibronectin on rat mast cells |
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Authors: | J Sasaki M Imanaka S Watanabe N Otsuka K Sugiyama |
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Institution: | (1) Department of Anatomy and Department of Pharmacology, Okayama University Medical School, 700 Okayama, (Japan) |
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Abstract: | Summary Rabbit anti-rat plasma fibronectin (pFN) causes histamine release from rat mast cells in the presence of complement. Fibronectin (FN) on rat mast cells, as shown by immuno-electron microscopy, is principally localized on cell folds, so they may play a role of attachment in the matrix of connective tissue.Acknowledgment. This work is supported by grants (No. 56770014 and No. 544018) from the Ministry of Education, Science and Culture of Japan. |
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