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Serotonin and 5-hydroxyindoleacetic acid concentrations in individual hypothalamic nuclei and other brain areas of rat |
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| Authors: | K Oomagari H Uchimura T Matsumoto H Yokoo M Hirano J S Kim T Nakahara |
| Institution: | (1) Department of Neuropsychiatry, Faculty of Medicine, Kyushu University, Maidashi 3-1-1, 812 Fukuoka, (Japan);(2) Laboratory of Neurochemistry, Hizen National Mental Hospital, Kanzaki, 842-01 Saga, (Japan);(3) Department of Chemistry, Faculty of Science, Kyushu University, Hakozaki, 812 Fukuoka, (Japan) |
| Abstract: | Summary Serotonin and 5-hydroxyindoleacetic acid (5-HIAA) were measured in individual nuclei of rat hypothalamus and other brain areas using HPLC with electrochemical detection. 5-HIAA levels were first demonstrated in hypothalamic and some discrete brain areas. The 5-HIAA/5-HT ratio was highest in the n. caudatus putamen, high in the n. ventromedialis and lowest in the n. suprachiasmaticus. |
| Keywords: | Rat brain brain rat hypothalamus rat serotonin 5-hydroxyindoleacetic acid |
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