Prevention of enteral radiocesium absorption by hexacyanoferrates(II) in piglets |
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| Authors: | P Nielsen R Fischer H C Heinrich A A Pfau |
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| Institution: | Institut für Physiologische Chemie, Universit?tskrankenhaus Eppendorf, Hamburg, Federal Republic of Germany. |
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| Abstract: | The efficacy of different hexacyanoferrates(II) in preventing the enteral absorption of 134Cs was studied in piglets. As compared to the controls, oral application of 134Cs together with KFeFe(CN)6], NH4FeFe(CN)6], or Fe4Fe(CN)6]3 resulted in a strong reduction of the 134 Cs-uptake by more than 97%. The decrease in enteral absorption depends on the dose of administered hexacyanoferrate(II), whereas differences between the compounds under study were small. The biological half-life of 134Cs in non-hexacyanoferrate(II) treated piglets was 21.6 +/- 3.3 days (mean +/- SD). |
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