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| 卷烟主流烟气中酚类化合物的LC-MS/MS法测定 | |
| 引用本文： | 肖志翔,杨翠清,丁时超,银董红.卷烟主流烟气中酚类化合物的LC-MS/MS法测定[J].湖南师范大学自然科学学报,2009,32(4). |
| 作者姓名： | 肖志翔 杨翠清 丁时超 银董红 |
| 作者单位： | 1. 郑州轻工业学院食品与生物工程学院,中国郑州,450002 2. 湖南中烟工业有限责任公司技术中心,中国长沙,410007 3. 湖南中烟工业有限责任公司技术中心,中国长沙 410007;湖南师范大学化学化工学院,中国长沙 410081 |
| 基金项目： | 湖南中烟工业公司科技计划项目 |
| 摘 要： | 采用1%醋酸水溶液直接对收集主流烟气的剑桥滤片进行简单的超声萃取,过滤后的萃取液用LC-MS/MS ESI负离子模式进行分析.研究了主流烟气中6种简单酚类化合物的LC-MS/MS法的液相操作条件、质谱分析测定参数、仪器最低检测限值、回收率、重复性、定量分析曲线等,为卷烟主流烟气中酚类化合物的定量检测建立了一种快速分析新方法,该方法具有前处理简单、分析时间短、数据可靠和回收率高等特点. |
| 关 键 词： | 卷烟 主流烟气 酚类化合物 检测 |
LC-MS/MS Determination of Major Phenolic Compounds in Mainstream Cigarette Smoke |
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| XIAO Zhi-xiang,YANG Cui-qing,DING Shi-chao,YIN Dong-hong.LC-MS/MS Determination of Major Phenolic Compounds in Mainstream Cigarette Smoke[J].Journal of Natural Science of Hunan Normal University,2009,32(4). | |
| Authors: | XIAO Zhi-xiang YANG Cui-qing DING Shi-chao YIN Dong-hong |
| Abstract: | The mainstream cigarette smoke collected in the Cambridge filter pad was ultrasonic extracted by 1% acetic acid solution with no other pretreatment.The extract was filtered through a 0.45 μm membrane filter,and then was analyzed by LC-MS-MS system operated in electrospray negative ion mode.6 phenolic compounds in mainstream cigarette smoke were determined by optimizing the LC analysis conditions and MS parameters.The limit of quantification,recoveries,repeatability,and the quantitative analysis were obtained at the optimal analysis conditions.In conclusion,a new method of rapid quantitative determination of phenolic compounds in mainstream cigarette smoke has been established in this paper.The method has the features of simple pretreatment,rapid analysis,preciseness and credibility of the analysis.as well as high recoveries. |
| Keywords: | LC-MS/MS LC-MS/MS cigarette mainstream smoke phenolic compounds determination |
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