|
|||||
|
|
| 大豆黄酮对衰老小鼠脑组织抗氧化能力的影响 | |
| 引用本文： | 刘文,陆军,陈龙,单群,才金玲,沈露露,程超,郑元林.大豆黄酮对衰老小鼠脑组织抗氧化能力的影响[J].徐州师范大学学报(自然科学版),2004,22(4):41-44. |
| 作者姓名： | 刘文 陆军 陈龙 单群 才金玲 沈露露 程超 郑元林 |
| 作者单位： | 1. 徐州师范大学,江苏省药用植物生物技术重点实验室,江苏,徐州,221116 2. 徐州师范大学,生命科学学院,江苏,徐州,221116 3. 江苏省资源生物技术重点实验室,江苏,南京,210008 |
| 基金项目： | 江苏省重点实验室开放基金资助项目(KJS02024)，江苏省教育厅自然科学基金资助项目(98KJB180003，03KJD180219) |
| 摘 要： | 用大豆黄酮(daidzein)灌喂脑老化模型小鼠．5周后分别测定各组小鼠脑组织的超氧化物歧化酶(SOD)活性、乳酸脱氢酶(LDH)活性、总抗氧化能力(T-AOC)和丙二醛(MDA)含量．结果显示：大豆黄酮能够使脑老化模型小鼠的SoD的活力和T-AOC显增加，LDH的活力和MDA的含量极显下降，其中T-AOC和MDA超过了生理盐水对照组，暗示大豆黄酮除了通过提高SOD的活性来增加机体抗氧化能力外，还存在通过其他的途径来提高机体的抗氧化能力，并且大豆黄酮在抗氧化水平上还有一定的剂量效应． |
| 关 键 词： | 脑组织 脑老化 模型小鼠 抗氧化能力 衰老小鼠 MDA 含量 大豆黄酮 活力 活性 |
| 文章编号： | 1007-6573(2004)04-0041-04 |
| 修稿时间： | 2004年4月22日 |
The Effects of Daidzein on the Antioxidation Level in Brain of Aged Mice |
|
| LIU Wen,LU Jun,CHEN Long,SHAN Qun,CAI Jin-ling,SHEN Lu-lu,CHENG Chao,ZHENG Yuan-lin mal University,Xuzhou,Jiangsu,China, .School of Life Science,Xuzhou Normal University,Xuzhou,Jiangsu,China, ngsu,China.The Effects of Daidzein on the Antioxidation Level in Brain of Aged Mice[J].Journal of Xuzhou Normal University(Natural Science Edition),2004,22(4):41-44. | |
| Authors: | LIU Wen LU Jun CHEN Long SHAN Qun CAI Jin-ling SHEN Lu-lu CHENG Chao ZHENG Yuan-lin mal University Xuzhou Jiangsu China School of Life Science Xuzhou Normal University Xuzhou Jiangsu China ngsu China |
| Institution: | LIU Wen~1,LU Jun~2,CHEN Long~3,SHAN Qun~2,CAI Jin-ling~2,SHEN Lu-lu~2,CHENG Chao~2,ZHENG Yuan-lin~2 mal University,Xuzhou,Jiangsu,221116,China, 2.School of Life Science,Xuzhou Normal University,Xuzhou,Jiangsu,221116,China, ngsu,210008,China) |
| Abstract: | Several groups of brain-aged model mice were fed with daidzein for 5 weeks and then their activities of SOD and LDH,the content of MDA,and T-AOC were determined.The results show that daidzein can remarkably increase their acticity of SOD and T-AOC,and decrease the activity of LDH and the content of MDA,where the T-AOC and MDA are found higher than the conparison group with physiological saline.This suggests that for daidzein there are some other ways to raise the antioxidation of an organism body besides increasing the activity of SOD.Moreover,there is a dose-effect connected with the antioxidation level. |
| Keywords: | daidzein aged mice SOD LDH T-AOC MDA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |