紫色甘薯多糖对荷瘤小鼠抗肿瘤活性的影响

以荷瘤S180小鼠为实验对象, 研究了紫色甘薯多糖对S180荷瘤小鼠肿瘤的体内抑制、免疫器官的影响. 结果表明: 紫色甘薯多糖对S180荷瘤小鼠的抑瘤率可达40%左右(P<0 01); 低剂量的紫色甘薯多糖与5 氟尿嘧啶(5 FU)配伍使用, 能提高荷瘤小鼠抑瘤率, 对5 FU所致的荷瘤小鼠胸腺、脾脏质量萎缩有明显的保护作用, 对白细胞的减少有一定的拮抗作用.

Effect of Polysaccharide in Purple Sweet Potato on the Antitumor Activity of Cancer Bearing Mice

The antitumor effect of polysaccharide in purple sweet potato on the Sarcoma 180 (S (180)) bearing mice was observed. The inhibitory rate to S (180) tumor and immune function of mice was determined. Results showed that polysaccharide extracted from purple sweet potato had markedly effect of inhibitory tumor on the cancer S (180) bearing mice, and its inhibitory rate would be 40% (P<0. 01); the mixture therapy group of low dose polysaccharide (200mg/kg) and 5-fluorine uracil (5-FU) would inhibit tumor, and had obviously protective effect on the thymus and spleen weights atrophy resulted from 5-FU, and had antagonism of the decrease in white cell amount.