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| 烟碱和一氧化碳对大鼠学习记忆及脑发育的影响 | |
| 引用本文： | 季淑梅,秦惠霞,李志彪.烟碱和一氧化碳对大鼠学习记忆及脑发育的影响[J].河北科技大学学报,2003,24(1):91-94. |
| 作者姓名： | 季淑梅 秦惠霞 李志彪 |
| 作者单位： | 1. 河北医科大学生理组,河北石家庄,050017 2. 石家庄市第四中学,河北石家庄,050011 3. 河北制药股份有限公司,河北石家庄,050041 |
| 摘 要： | 通过观察烟碱和一氧化碳(CO)对大鼠学习记忆和脑发育的影响,利用Y型迷宫测试学习记忆,利用电镜技术观测脑超微结构。得出烟碱可使学习记忆能力下降(P<0.05),使大脑皮层厚度(P<0.05)及突触数密度(P |
| 关 键 词： | 烟碱 一氧化碳(CO) 学习 记忆 大脑皮层 |
| 文章编号： | 1008-1542(2003)01-0091-04 |
| 修稿时间： | 2001年8月29日 |
Effects of Nicotine and Carbon Monoxide on Rote Learning and Development of Rat's Brain |
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| JI Shu-mei,QIN Hui-xia,LI Zhi-biao.Effects of Nicotine and Carbon Monoxide on Rote Learning and Development of Rat''''s Brain[J].Journal of Hebei University of Science and Technology,2003,24(1):91-94. | |
| Authors: | JI Shu-mei QIN Hui-xia LI Zhi-biao |
| Abstract: | In order to investigate the effects of nicotine and carbon monoxide on learning and development of rats' brain. Y-maze device are adopted to study the rote learning and electro microscope technology is utilized for observing supermicro-structure of brain. The results show that nicotine decreases the learning and memory function(p<0. 05).reduces corticocerebral thickness (p<0. 05)and the density of synapses(p<0. 01),changes the percentage of synapse Gray Ⅰ and Gray Ⅱ and the precentage of synapse Gray Ⅰ is increased(p<0. 05); while the percentage of synapse Gray Ⅱ is reduced,carbon monoxide has slight influence on them. These datas suggest that nicotine the smoke of cigarette,may have harmful effect on rote learning and developament of rat's brain. |
| Keywords: | nicotine carbon monoxide rote learning cortex of cerebrum |
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