花状Ni(OH)2微球的制备及其对尿酸的快速检测

采用微波辅助水热法制备了均匀分级的氢氧化镍(Ni(OH)₂)微球，通过X射线衍射(XRD)仪、扫描电子显微镜(SEM)和透射电子显微镜(TEM)对Ni(OH)₂的组成和形貌进行了表征. Ni(OH)₂微球的平均直径约1.6 μm，复杂的花状结构使其具有较大的比表面积.将微球制备成Ni(OH)₂修饰的玻碳电极，并将其用于0.1 mol/L NaOH溶液中尿酸(UA)的检测，该电极具有良好的电催化活性.这种传感器表现出较宽的线性范围(0.1~1.5 mmol/L)和高灵敏度(475.71 μA ·L/(mmol ·cm2))，且有较低的检出限(1.8 μmol/L).利用电化学测试对内源性干扰物进行检验，发现Ni(OH)₂微球修饰电极对UA的选择性较好.结果表明:Ni(OH)₂微球在研发无酶尿酸传感器方面具有重要的应用潜力.

Synthesis of Flower-Like Ni(OH)2 Microsphere for the Rapid Detection of Uric Acid

Uniform hierarchical nickel hydroxide microspheres were successfully synthesized via a microwave-assisted hydrothermal process. The composition and morphology of the composites were determined with X-ray diffraction(XRD), scanning electron microscopy(SEM), and transmission electron microscopy(TEM). The nickel hydroxide microspheres had an average diameter of 1.6 μm and a flower-like structure, which meant a large specific surface area. Furthermore, the nickel hydroxide modified glassy carbon electrode was built and utilized for the detection of uric acid (UA) in a 0.1 mol/L NaOH, where it indicated excellent electrocatalytic activity. This biosensor exhibited a wide linear range from 0.1 mmol/L to 1.5 mmol/L with a high sensitivity of 475.71 μA ·L/(mmol ·cm2)and a low detection limit of 1.8 μmol/L. It was found in an electrochemical test that the Ni(OH)₂ microspheres-modified electrode had good selectivity. All the results demonstrated that the Ni(OH)₂ microspheres possessed significant potential for application to the development of non-enzymatic sensors for UA detection.