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聚乙二醇活性酯的制备
引用本文:田芳,韩灵翠,陈恬生.聚乙二醇活性酯的制备[J].太原理工大学学报,1995(2).
作者姓名:田芳  韩灵翠  陈恬生
作者单位:太原工业大学,北京理工大学
摘    要:本文研究了制备聚乙二醇活性酯的方法。首先将聚乙二醇(PEG)转化为羧酸,然后活化成为活性酯,该活性酯用于修饰SOD.此方法所用时间短,条件易掌握,与SOD连接效果较好。

关 键 词:聚乙二醇(PEG)  聚乙二醇活性酯  活化  修饰  超氧化物歧化酶(SOD)

Preparation of Active Ester of Polyethyen Glycol
Tian Fang,Han Lingcui.Preparation of Active Ester of Polyethyen Glycol[J].Journal of Taiyuan University of Technology,1995(2).
Authors:Tian Fang  Han Lingcui
Institution:Tian Fang;Han Lingcui(Taiyan Uniuersity of Technology)Chen Tiansheng(Beijing Institute of Technology)
Abstract:A method for preparation of active ester of polyethylene is reported.Procedures for the preparation included two steps. At first, the terminal hydroxyl group of PEG was changed into carboxylic acid. Then the product was activated with dicyclohexyl carbondimide(DCC)and p-nitrophenol to form an active ester. The active ester of PEG was used to couple with superoxide dismutase(SOD).It took short time and was easy to obtain the expect product.
Keywords:polyethylene glycol(PEG)  active ester of PEG  activate  modification  superoxide dismutase(SOD)
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