| 电针对佐剂性关节炎大鼠炎症局部c-fos表达的影响 |
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| 引用本文： | 赵仓焕,许建阳.电针对佐剂性关节炎大鼠炎症局部c-fos表达的影响[J].暨南大学学报,1999,20(6):92-94. |
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| 作者姓名： | 赵仓焕 许建阳 |
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| 作者单位： | 暨南大学医学院第一附属医院针灸科!广东广州510630(赵仓焕)，南京中医药大学针灸系!江苏南京210029(许建阳) |
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| 摘 要： | 目的：观察电针（ＥＡ）对炎症痛模型佐剂性关节炎（ＡＡ）大鼠炎症局部ｃ－ｆｏｓ表达的影响，以探讨针刺对炎症痛的外周镇痛机制。方法：以福氏完全佐剂造成炎症痛模型ＡＡ、选取悬钟、昆仑穴ＥＡ治疗，采用免疫组织化学方法检测ｃ－ｆｏｓ表达。结果：ＥＡ可以抑制ＡＡ大鼠炎症局部ｃ－ｆｏｓ的表达。结论：ｃ－ｆｏｓ可能参与了ＥＡ对炎症痛的外周镇痛作用。
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| 关 键 词： | 电针 佐剂性关节炎 c－fos 炎症痛 外周镇痛机制 |
| 修稿时间： | 1999-08-18 |
Effects of electroacupuncture on c-fos expression in inflamed location of adjuvant arthritic rats |
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| ZHAOCang- huan,XUjian -yang.Effects of electroacupuncture on c-fos expression in inflamed location of adjuvant arthritic rats[J].Journal of Jinan University(Natural Science & Medicine Edition),1999,20(6):92-94. |
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| Authors: | ZHAOCang- huan XUjian -yang |
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| Institution: | ZHAOCang- huan1,XUjian -yang2 |
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| Abstract: | Aim To seek for
peripheral mechanism of electroacupuncture(EA) analgesia, observed effects of EA on c-fos
expression in inflamed location in adjuvant arthritic(AA) rats of inflammatory-pain model.
Methods Injected Freund's complete adjuvant into the right hind paw of
rats to produce AA model, stimulated Xuanzhong and Kunlun points with EA, adopted avidin
biotin-peroxidase complex technique(ABC) to detect c-fos expression. Results
EA may modify c-fos expression in inflamed location in AA rats. Conclusion
C-fos probably involve peripheral action of EA analgesia on inflammatory-pain. |
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| Keywords: | EA AA c-fos inflammatory- pain peripheralanalgesic mechanism |
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