CT在诊断及随访足月新生儿缺氧缺血性脑病中的价值

目的：探讨CT在诊断及随访足月新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)中的价值。方法：回顾分析有围产期窒息史，I临床诊断为不同程度HIE的足月新生儿220例的CT资料，其中。102例进行了CT复查。结果：220例HIE中，轻度128例，中度63例，重度29例；102例CT复查中，正常47例，外部性脑积水35例，胼胝体发育不全11例，脑软化灶22例，脑萎缩13例，脑穿通畸形15例，脑白质减少10例，死亡2例。轻度者复查表现为正常或外部性脑积水，而中、重度者复查则多表现为上述其它各种不可逆后遗症。结论：(1)CT在诊断和随访HIE中具有重要价值；(2)HIE的预后与CT分度有关，轻度者一般预后良好，中、重度者预后较差。

Diagnostic and follow-up value of CT scan on full-term neonatal hypoxic ischemic encephalopathy

Aim: To eveluate the diagnostic and follow-up value of CT scan on full-term neonatal HIE(hypoxic ischemic encephalopathy). Methods: 220 full term neonatal with asphyxial perinatal asphy xia were analyzed retrospectively, and HIE was diagnosed. They were all taken initial CT scanning, follow-up study was carried out in 102 cases. Results: In 220 cases, 128 cases had mild HIE, 63 cases had moderate HIE, 29 cases had severe HIE. Follow-up study showed on CT scan: Normal in 47 cases, external hydrocephalus in 35 cases, dysplasia of corpus callosum in 11 cases, encephalomalacia in 22 cases, cerebral atrophy in 13 cases, porencephaly in 15 cases, white matter decreased 10 cases, 2 patients died. Cases of moderate, severe HIE had corresponding clinical manisfications. Conclusion:(1) CT scan play an important role in the diagnosis and follow-up of HIE in full-term neonates with HIE. (2) Prognosis of HIE was related to the degree of abnomal manifestations on CT.