| 槲皮素镧配合物对S.Pombe细胞生长代谢热动力学的影响 |
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| 引用本文： | 蒋建宏,周菊峰,胡钞粟,肖碧源,肖圣雄,李强国.槲皮素镧配合物对S.Pombe细胞生长代谢热动力学的影响[J].井冈山大学学报（自然科学版）,2015(2):20-24. |
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| 作者姓名： | 蒋建宏 周菊峰 胡钞粟 肖碧源 肖圣雄 李强国 |
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| 作者单位： | 湘南稀贵金属化合物及其应用湖南省重点实验室, 湖南, 郴州 423043;湘南学院化学与生命科学系, 湖南, 郴州 423043,湘南学院化学与生命科学系, 湖南, 郴州 423043,湘南学院化学与生命科学系, 湖南, 郴州 423043,湘南学院化学与生命科学系, 湖南, 郴州 423043,湘南稀贵金属化合物及其应用湖南省重点实验室, 湖南, 郴州 423043;湘南学院化学与生命科学系, 湖南, 郴州 423043,湘南稀贵金属化合物及其应用湖南省重点实验室, 湖南, 郴州 423043;湘南学院化学与生命科学系, 湖南, 郴州 423043 |
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| 基金项目： | 国家自然科学基金项目(21273190);湖南省科技计划项目(2013FJ3033;2012TP4021-6;2010FJ3053);湘南学院科研基金项目(2013YJ36;2014XJ52);湘南学院大学生研究性学习和创新性实验计划项目(校发[2013]15号);湘南学院大学生科研课题项目(校发[2014]10号) |
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| 摘 要： | 采用八通道微量热法探讨槲皮素镧配合物对粟酒裂殖酵母细胞生长代谢热动力学的影响。测定在槲皮素镧配合物作用下S.Pombe细胞的生长代谢产热曲线,并研究其生长速率常数(k)、最大发热功率(pmax)、达最大发热功率时间(tmax)和抑制率(I)等热动力学参数。微量热结果表明:随着槲皮素镧配合物浓度c的增大,最大发热功率pmax和速率常数k减小;达最大发热功率时间tmax和抑制率I增大。研究表明槲皮素镧配合物对粟酒裂殖酵母细胞生长代谢产生了抑制作用。
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| 关 键 词： | 槲皮素镧配合物 微量热法 粟酒裂殖酵母细胞 |
| 收稿时间： | 2014/11/20 0:00:00 |
| 修稿时间： | 2015/2/16 0:00:00 |
THERMODYNAMIC EFFECT OF THE QUERCETIN LANTHANUM COMPLEXES ON PROLIFERATION OF SCHIZOSACCAROMYCES POMBE CELLS |
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| JIANG Jian-hong,ZHOU Ju-feng,HU Chao-su,XIAO Bi-yuan,XIAO Sheng-xiong and LI Qiang-guo.THERMODYNAMIC EFFECT OF THE QUERCETIN LANTHANUM COMPLEXES ON PROLIFERATION OF SCHIZOSACCAROMYCES POMBE CELLS[J].Journal of Jinggangshan University(Natural Sciences Edition),2015(2):20-24. |
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| Authors: | JIANG Jian-hong ZHOU Ju-feng HU Chao-su XIAO Bi-yuan XIAO Sheng-xiong and LI Qiang-guo |
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| Institution: | Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds Research and Application, Chenzhou, Hunan 423043, China;Department of Chemistry and Life Sciences, Xiangnan University, Chenzhou, Hunan 423043, China,Department of Chemistry and Life Sciences, Xiangnan University, Chenzhou, Hunan 423043, China,Department of Chemistry and Life Sciences, Xiangnan University, Chenzhou, Hunan 423043, China,Department of Chemistry and Life Sciences, Xiangnan University, Chenzhou, Hunan 423043, China,Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds Research and Application, Chenzhou, Hunan 423043, China;Department of Chemistry and Life Sciences, Xiangnan University, Chenzhou, Hunan 423043, China and Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds Research and Application, Chenzhou, Hunan 423043, China;Department of Chemistry and Life Sciences, Xiangnan University, Chenzhou, Hunan 423043, China |
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| Abstract: | To study the thermodynamic effect of the quercetin lanthanum complexes on proliferation of Schizosaccharomyces pombe cells, eight channels microcalorimetry was performed to determine the heat production curve of cell proliferation and metabolism after the quercetin lanthanum complexes was added, and thermodynamic parameters such as growth and metabolism rate constant (k), the maximum heating power (pmax), the max heating power time (tmax) and inhibition rate (I) were also investigated. The microcalorimetric results showed that the maximum heating power pmax and rate constant k decreased but the max heating power time tmax and inhibition rate I enlarged with the increasement of concentration c of quercetin lanthanum complexes. It could be concluded that quercetin lanthanum complexes inhibited the cell growth and metabolism of S. pombe. |
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| Keywords: | quercetin lanthanum complexes microcalorimetry Schizosaccharomyces pombe cell |
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