| Design and application of 60mer oligonucleotide microarray in SARS coronavirus detection |
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| 作者姓名： | SHI Rong MA Wenli WU Qinghua ZHANG Bao SONG Yanbin GUO Qiuye XIAO Weiwei WANG Yan & ZHENG Wenling . Institute of Molecular Biology First Military Medical University Guangzhou China . |
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| 作者单位： | SHI Rong,Ma Wenli,WU Qinghua,ZHANG Bao,Song Yanbin,GUO Qiuye,Xiao Weiwei,WANG Yan(Institute of Molecular Biology, First Military Medical University, Guangzhou 510515, China);Zheng Wenling(Department of Medical Research, Guangzhou Liu Hua Qiao Hospital, Guangzhou 510010, China) |
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| 摘 要： | In April 2003, a novel coronavirus1,2] which was associated with cases of Severe Acute Respiratory Syn-drome (SARS) was first isolated and sequenced in Canada. The genome of SARS coronavirus (SARS-CoV) is 297273] nucleotides in length and has 11 known open reading frames (ORFs). Although the genome organiza-tion of this virus is similar to that of other coronaviruses, phylogenetic analyses and sequence alignment show that SARS-CoV is not closely related to any of the previously ch…
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| 收稿时间： | 2003-05-13 |
| 修稿时间： | 2003-06-11 |
Design and application of 60mer oligonucleotide microarray in SARS coronavirus detection |
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| SHI Rong,MA Wenli,WU Qinghua,ZHANG Bao,SONG Yanbin,GUO Qiuye,XIAO Weiwei,WANG Yan & ZHENG Wenling . Institute of Molecular Biology,First Military Medical University,Guangzhou ,China, ..Design and application of 60mer oligonucleotide microarray in SARS coronavirus detection[J].Chinese Science Bulletin,2003,48(12):1165-1169. |
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| Authors: | Shi Rong Ma Wenli Wu Qinghua Zhang Bao Song Yanbin Guo Qiuye Xiao Weiwei Wang Yan Zheng Wenling |
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| Institution: | e-mail: wenli@ fimmu.edu.cn |
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| Abstract: | |
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| Keywords: | SARS coronavirus oligonucleotide microarray RD tech-nique fluorescent labeling molecular hybridization |
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