New strategies for the repair of spinal cord injury |
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Authors: | Zhourui Wu Ziru Zhao Yan Yu Xiao Hu Wei Xu Zhili Zeng Yi Eve Sun Liming Cheng |
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Institution: | 1. Department of Spine Surgery, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China 2. Translational Stem Cell Center, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China
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Abstract: | Spinal cord injury (SCI) leads to several neurologic damages to patients with sensory and motor function loss. Although some inspiring results were reported in animal, even in non-human primate models, the clinical translation of these research achievements barely move forward for the SCI patients. This review mainly focused on the pathogenesis of the primary and secondary injury, the clinical therapies and the new technologies in spinal cord injury. Moreover, the key scientific issues on this field were discussed in the review. Finally, some suggestions were proposed for the scientific and clinical researches. |
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Keywords: | Spinal cord injury Secondary injury Repair Regeneration Stem cells |
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