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Identification and bioinformatics analysis of pseudogenes from whole genome sequence of Phaeodactylum tricornutum |
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| Authors: | ChangMian Ji AiYou Huang WenLing Liu GuangHua Pan GuangCe Wang |
| Institution: | 15174. Tianjin Key Laboratory of Marine Resources and Chemistry, College of Marine Science and Engineering, Tianjin University of Science and Technology, Tianjin, 300457, China 25174. Institute of Oceanology, Chinese Academy of Sciences (IOCAS), Qingdao, 266071, China 35174. Graduate University of Chinese Academy of Sciences, Beijing, 100049, China |
| Abstract: | Pseudogenes share sequence similarities with functional genes, but in general they have lost their protein-coding ability. The identification of pseudogenes is a very important step in genome annotation. Phaeodactylum tricornutum is a marine diatom that is rich in polyunsaturated fatty acids (PUFAs). The genome of P. tricornutum has been completely sequenced. To identify pseudogenes in P. tricornutum, we developed a pipeline to discover and characterize pseudogenes. We identified a total of 1654 ‘true’ processed pseudogenes, 714 duplicated pseudogenes and 4729 pseudogene fragments. The results of the bioinformatics analysis indicated that the genome sequence of P. tricornutum contained many pseudogenes and pseudogene fragments. |
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