| On the “plasticity”of adult stem cells and its application in regenerative medicine |
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| 作者姓名： | WANGYunfang PEIXuetao |
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| 作者单位： | DepartmentofStemCellBiology,BeijingInstituteofTransfusionMedicine,Beijing100850,China |
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| 基金项目： | 国家高技术研究发展计划(863计划)，国家重点基础研究发展计划(973计划) |
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| 摘 要： | In recent years, with the increasingly further studies on embryonic stem cells and the recognition of the biologic characteristics of adult stem cells, it has been discovered that adult stem cells have another phenomenon of “plasticity” in addition to the characteristics of strong potential for self-renewal, proliferation and multi-differentiation, which brings us the hope for regenerative medicine—renewing new organ or tissue cells to replace those damaged by injury or diseases. Although the mechanism of “plasticity” and its application in the regenerative medicine are still in doubt, thorough exploration in these subjects would open up broad prospects for the use in cell and tissue engineering in the near future.
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| 关 键 词： | 胚胎干细胞 再生医学 可塑性 病理学 |
| 收稿时间： | 2002-12-19 |
| 修稿时间： | 2003-02-10 |
On the “plasticity” of adult stem cells and its application in regenerative medicine |
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| WANGYunfang PEIXuetao.On the “plasticity” of adult stem cells and its application in regenerative medicine[J].Chinese Science Bulletin,2003,48(13):1392-1396. |
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| Authors: | Yunfang Wang Xuetao Pei |
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| Institution: | e-mail: peixt@ nic.bmi.ac.cn |
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| Abstract: | In recent years, with the increasingly further studies on embryonic stem cells and the recognition of the biologic characteristics of adult stem cells, it has been discovered that adult stem cells have another phenomenon of "plasticity" in addition to the characteristics of strong poten-tial for self-renewal, proliferation and multi-differentiation, which brings us the hope for regenerative medicine --renewing new organ or tissue cells to replace those damagedby injury or diseases. Although the mechanism of "plastic-ity" and its application in the regenerative medicine are still in doubt, thorough exploration in these subjects would open up broad prospects for the use in cell and tissue engineering in the near future. |
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| Keywords: | adult stem cells embryonic stem cells plasticity environmental signal regenerative medicine |
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