辛夷芳香性双四氢呋喃成分研究

为阐明辛夷药材中芳香性双四氢呋喃化学成分,采用溶剂萃取、高速逆流分段、大孔树脂和半制备高效液相色谱分离和纯化,得到了4个高纯度芳香性双四氢呋喃木脂素单体化合物.通过1H NMR、13C NMR、MS等现代波谱学方法分别鉴定为:松脂醇二甲醚(1),木兰脂素(2),里立脂素B二甲醚(3),epimagnolin B(4).辛夷芳香性成分的鉴定为其在医药、食品工业中的应用提供了更好的理论依据.

Study on the Aromatic Ditetrahydrofuran Constituents from Magnolia denudata Desr.

In order to investigate the ditetrahydrofuran constituents of spicery from Magnolia denudata Desr. , solvent extraction, high speed counter-current chromatography (HSCCC), macroporous resin and semi-preparative high performance liquid chromatography (HPLC) were used and four highly purified aromatic lignans were obtained. They were identified as pinoresinol dimethy ether (1), magnolin (2), lirioresinol-B dimethyl ether (3) and epimagnolin B (4).The structures of these compounds were elucidated based on the ¹H NMR, ¹³C NMR,and MS characterization. The identification of these aromatic components of Magnolia denudate Desr. provided a theoretical basis for its application in medicine and food industry.