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蚓激酶对30周糖尿病模型大鼠胃肌间丛神经元尼氏体的影响
引用本文:陆英杰,连至诚,钟毅,赵自明.蚓激酶对30周糖尿病模型大鼠胃肌间丛神经元尼氏体的影响[J].佛山科学技术学院学报(自然科学版),2012,30(3):79-81.
作者姓名:陆英杰  连至诚  钟毅  赵自明
作者单位:1. 佛山科学技术学院动物医学系,广东佛山,528231
2. 广州中医药大学脾胃研究所,广东广州,510405
3. 广州第二中医院,广东广州,510400
4. 广东省中医研究所,广东广州,510400
摘    要:应用链脲佐菌素(Streptozotocin,STZ)建立SPF级SD大鼠糖尿病模型,糖尿病大鼠随机分为蚓激酶干预组和模型组。实验持续30周后,采用甲苯胺蓝染色方法对糖尿病30周大鼠、正常对照组及蚓激酶干预组的胃肌间丛神经元尼元氏体进行检测。结果:糖尿病30周模型大鼠尼氏体数量比正常组少(P〈0.01);而蚓激酶组数量...

关 键 词:胃肌间丛  神经元尼氏体  糖尿病大鼠  蚓激酶

The effect of Lumbrokinase on the neuron Nissl bodies in the gastric muscle plexus of diabetic rats
LU Ying-jie,LIAN Zhi-cheng,ZHONG Yi,ZHAO Zi-ming.The effect of Lumbrokinase on the neuron Nissl bodies in the gastric muscle plexus of diabetic rats[J].Journal of Foshan University(Natural Science Edition),2012,30(3):79-81.
Authors:LU Ying-jie  LIAN Zhi-cheng  ZHONG Yi  ZHAO Zi-ming
Institution:1.Department of Veterinary Medicine,Foshan University,Foshan 528231,China;2.The Research Department of the Spleen and Stomach,Guangzhou Traditional Chinese Medicine University,Guangzhou 510405,China;3.The Second Chinese Medical Hospital of Guangzhou,Guangzhou 510400,China;4.The Institute of Traditional Chinese Medicine of Guangdong province,Guangzhou 510400,China)
Abstract:Objective To observe the treatment effect of Lumbrokinase on the neuron Nissl bodies in the gastric muscle plexus of diabetic rats.Methods An experiment on the SPF models established by using streptozotocin(STZ) and diabetic rats which were randomly put into the control and the Lumbrokinase trial groups was carried out.The effect was examined through the use of toluidine in 30 weeks.Results The amount of neuron Nissl bodies of the models was less than that of the control group(P<0.01) while the amount of neuron Nissl bodies of the Lumbrokinase trial group was more than that of the models(P<0.01).There was a difference between the control and the trial groups(P<0.05).Conclusion The decrease of the amount of neuron Nissl bodies of the models indicated the neuron was damaged and Lumbrokinase was effective in protecting neuron.
Keywords:gastric muscle plexus  neuron Nissl bodies  diabetic rat  Lumbrokinase
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