美国野水鸭I型副黏病毒病HI免疫抗体消长规律试验

试验采用鸭副黏病毒GSFY株（A苗）、GSBY株（E苗）油乳剂灭活疫苗和鸡新城疫NH株（N苗）油乳剂灭活疫苗对7d、14d和21d的美国野水鸭分别进行不同剂量和不同次数的免疫，检测各实验组鸭的HI抗体变化情况。结果显示，美国野水鸭分别免疫后，HI抗体A苗21d和E苗14d时分别达4．55log和5．27log以上，维持时间为35～42d以上。N苗除3次免疫组21d时达到4．0log以上维持时间21～28d外，1次和2次免疫组均不能达到4．0log的抗体水平。结果表明，对美国野水鸭作I型副黏病毒病灭活疫苗免疫具有良好的免疫效果，尤以3次免疫为佳．3个不同来源毒株的灭活疫苗以GSBY株油乳剂灭活疫苗的免疫效果最好。

Variation of HI immune antibody to param- yxovirus type I in American wild water duck

Oil adjuvant inactivated ,,occines of Duck Paramyxovirus （GSFY strain from Muscovy Duck and GSBY strain from Cherry Valley Duck）and Chicken Newcastle Disease （NH strain） were inoculated to 7 d, 14 d, 21 d American wild water ducks at different doses and times. The variation of HI antibody were investigated in all the ducks. The results were： HI antibody A and E of American wild water duck was over 4.55 log and 5.27 log at 21 d and 14 d after inoculation respectively and the level maintained over 35 ~ 42 d. HI antibody N arrived at 4. 0 log at 21 d after inoculation and maintained till 21-28 d for the group inoculated for 3 times, it did not arrive at the level of 4.0 log for the groups inoculated for only 1 time or 2 times. The results showed that the inactivated vaccines of Duck Paramyxovirus had good immune effects, especially for 3 times inoculation. The GSBYstrain of oil adjuvant inactivated vaccines had the best immune effects among the 3 strains.