| 松果有效成分研究——Ⅵ.红松与油松松塔及松子壳的抗癌活性 |
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| 引用本文： | 吕永俊,王士贤,彭芳,李好枝,刘光明.松果有效成分研究——Ⅵ.红松与油松松塔及松子壳的抗癌活性[J].大理学院学报,2008,7(2):1-2. |
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| 作者姓名： | 吕永俊 王士贤 彭芳 李好枝 刘光明 |
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| 作者单位： | 1. 大理学院药学院,云南大理,671000
2. 天津医药研究院肿瘤室,天津,300070 |
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| 摘 要： | 目的：研究松塔和松子壳的抗癌活性。方法：采用给小鼠接种肿瘤细胞法测定松塔和松子壳的抗癌活性。结果：从红松松塔的碱性水提取多糖（60mg/kg）CK—C,对S180抑瘤率为48.9%,而CK—DEF对U14的抑瘤率为36.0%和40.4%;对Hep A,CK—DEF作用优于环磷酰胺。结论：松塔和松子壳有效成分具有较好的抗癌作用。
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| 关 键 词： | 松果 抗癌活性 S180 U14 Hep A |
| 文章编号： | 1672-2345(2008)02-0001-02 |
| 修稿时间： | 2007年12月21 |
Studies on effective compositions of Pine cone Ⅵ.Antitumor activity of fractions from pine cone and pine nut shell of Pinus koraiensis Sieb et Zucc and P.tabulaeformis Carr. |
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| LU Yong-jun,WANG Shi-xian,PENG Fang,LI Hao-zhi,LIU Guang-ming.Studies on effective compositions of Pine cone Ⅵ.Antitumor activity of fractions from pine cone and pine nut shell of Pinus koraiensis Sieb et Zucc and P.tabulaeformis Carr.[J].Journal of Dali University,2008,7(2):1-2. |
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| Authors: | LU Yong-jun WANG Shi-xian PENG Fang LI Hao-zhi LIU Guang-ming |
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| Institution: | LU Yong-jun, WANG Shi-xian, PENG Fang, LI Hao-zhi, LIU Guang-ming (1. College of Pharmacy, Dali University, Dali, Yunnan 671000, China; 2. Tianjin Academy of Medicine Research,Tianjin 300070, China) |
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| Abstract: | Objective：To study the anti-tumor activity of fractions from pine cone and pine nut shell. Methods：The anti-tumor activity of the extract from pine cone and pine nut shell was measured by injecting tumor cells into mice. Results：CK-C of the poly saccharine fractions obtained by NaOH extraction from Pinus Koraiensis Sieb et Zucc showed the most potent anti-tumor activity by 60 mg/kg.d×7 for S180,and the inhibitory rate of tumor was 48.9% ;and CK-DEF was highest for U14,and the inhibitory rate of tumor was 36.0% and 40.4% ;and CK-DEF was better than Cylophamide for Hep A. Conclusion：The activity of fractions from pine cone and pine nut shell showed obvious anti-tumor action. |
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| Keywords: | pine cone anti-tumor activity S 180 U 14 Hep A |
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