| 阿司匹林对在体及离体气管平滑肌的影响 |
| |
| 引用本文： | 尤星,王振国,杨春丽,徐稳,张杰,张来春,彭芳.阿司匹林对在体及离体气管平滑肌的影响[J].大理学院学报,2007,6(10):1-2,9. |
| |
| 作者姓名： | 尤星 王振国 杨春丽 徐稳 张杰 张来春 彭芳 |
| |
| 作者单位： | 大理学院药学院药学专业,云南大理,671000 |
| |
| 基金项目： | 大理学院校科研和教改项目 |
| |
| 摘 要： | 目的:研究阿司匹林对在体及离体气管平滑肌的影响.方法:观察不同剂量的阿司匹林对乙酰胆碱/磷酸组织胺诱发在体及离体豚鼠气管平滑肌收缩的影响.结果:阿司匹林对乙酰胆碱/磷酸组织胺诱发的体内外气管平滑肌收缩的对抗作用具有明显的剂量差异,即随着剂量增加,阿司匹林对抗气管平滑肌收缩的作用越来越弱,而沙丁胺醇且有很好的扩张气管平滑肌的作用.结论:适宜浓度的阿司匹林具有扩张气管平滑肌的作用.
|
| 关 键 词： | 阿司匹林 离体 在体 气管平滑肌 |
| 文章编号： | 1672-2345（2007）10-0001-02 |
| 修稿时间： | 2007-06-15 |
The influence of Aspirin on the bronchia smooth muscle in vivo and in vitro |
| |
| YOU Xing,WANG Zhen-guo,YANG Chun-li,XU Wen,ZHANG Jie,ZHANG Lai-chun,PENG Fang.The influence of Aspirin on the bronchia smooth muscle in vivo and in vitro[J].Journal of Dali University,2007,6(10):1-2,9. |
| |
| Authors: | YOU Xing WANG Zhen-guo YANG Chun-li XU Wen ZHANG Jie ZHANG Lai-chun PENG Fang |
| |
| Institution: | College of Pharmacy, Dali University, Dali, Yunnan 671000, China |
| |
| Abstract: | Objective:To study the influence of aspirin on the bronchia smooth muscle in vivo and in vitro.Method: To observe the influence of different dosage of aspirin on the bronchia smooth muscle contraction in guinea pig induced by Ach / His.Result: The influence varies with different dosage.As the dosage of aspirin increased,its effect on the bronchia smooth muscle contraction got weaker,but salbutamol had good effect on the dilation of the bronchia smooth muscle.Conclusion: Aspirin of proper concentration can dilate the bronchia smooth muscle. |
| |
| Keywords: | Aspirin in vitro in vivo bronchia smooth muscle |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
