羟乙基淀粉预扩容用于腰-硬联合麻醉剖宫产术的临床观察

目的:观察在腰-硬联合麻醉剖宫产术中使用羟乙基淀粉预扩容的临床效果。方法:选择腰-硬联合麻醉(CSEA)下择期剖宫产手术60例,随机分为2组,HES组(n=30)给6%羟乙基淀粉130/0.4氯化钠注射液500 mL进行预扩容,LR组(n=30)给予乳酸钠林格注射液500 mL进行预扩容。观察两组患者麻醉后低血压、恶心呕吐、麻黄碱的用量及术中液体用量的情况。结果:HES组麻醉后低血压的发生率、麻黄碱的用量及术中液体用量均低于LR组,差异有统计学意义(P<0.05)。结论:羟乙基淀粉预扩容能更好维持剖宫产术中血流动力学的稳定,保障产妇和胎儿的安全。

Clinical Observation of Hydroxyethyl Starch Preload Undergoing Combined Spinal Epidural Anesthesia for Cesarean Section

Objective: To observe the clinical effects of hydroxyethyl starch preload undergoing combined spinal epidural anesthesia(CSEA) for cesarean section.Methods: Sixty cases of CSEA,scheduled for elective cesarean section,were randomly divided into two groups.The hydroxyethyl starch preload(HES) group(n=30) was given 6% hydroxyethyl starch 130/0.4 sodium chloride injection 500 mL pre-expansion.The sodium lactate ringer’s injection(LR) group(n=30) was given lactated ringer’s injection 500 mL pre-expansion.The hypotension after anesthesia,nausea and vomiting and the amount of ephedrine and intraoperative fluid as well in two groups were recorded.Results: The incidence rates of hypotension after anesthesia,as well as the nausea and vomiting,the amount of ephedrine and the amount of intraoperative fluid in HES group were statistically lower than that in the LR group,respectively.Conclusion: Hydroxyethyl starch preload could better maintain the hemodynamic stability during the cesarean section than sodium lactate ringer,and it could safeguard the safety of maternal and fetal.