| 孤独症儿童静息态脑电Gamma频段功能网络研究 |
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| 引用本文： | 孙金秀,匡光涛,王索刚.孤独症儿童静息态脑电Gamma频段功能网络研究[J].科学技术与工程,2016,16(20). |
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| 作者姓名： | 孙金秀 匡光涛 王索刚 |
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| 作者单位： | 天津医科大学生物医学工程与技术学院,武汉市儿童医院,天津医科大学生物医学工程与技术学院 |
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| 基金项目： | 国家自然科学基金项目（61175118）;天津市教委基金项目(20090101);湖北省卫生计生西医类一般项目（WJ2015MB247） |
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| 摘 要： | 有研究表明,孤独症儿童的功能障碍可能和脑电中的Gamma频段异常有关。通过采集17例孤独症儿童和17例正常儿童睁眼静息态脑电,利用定向传递函数方法计算导联间的因果连接,构建Gamma频段(35~50 Hz)功能网络。用图论方法分析两组差异。结果表明相同阈值下,孤独症儿童脑功能网络全局效率、局部效率以及节点度均低于正常对照组儿童。提示孤独症儿童认知、行为异常可能与其大脑Gamma频段连接较弱、信息整合效率较低有关。
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| 关 键 词： | 孤独症儿童，静息态脑电，脑功能网络，Gamma频段 |
| 收稿时间： | 2016/3/16 0:00:00 |
| 修稿时间： | 2016/3/16 0:00:00 |
A study of brain functional network based on resting state gamma EEG in children with autism |
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| Abstract: | Previous studies showed that dysfunction of children with autism may be associated with abnormal gamma oscillation. In this article, brain functional connectivity networks in gamma (35-50Hz) band were constructed through the directed transfer function on the eyes-open resting-state EEGs recorded from 17 autisms and 17 controls. The graph theory analyses were then applied to estimate group changes. Compared with the control group, the autism group showed lower global and local efficiency and lower node degree. In summary these changes in gamma band connectivity may be related to cognitive and behavioral abnormalities in children with autism. |
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| Keywords: | autism resting state EEG brain functional network Gamma oscillation |
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