| 自由进食高脂类食物后大鼠血流变和D-二聚体变化的研究 |
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| 引用本文： | 张冬青,汪德清.自由进食高脂类食物后大鼠血流变和D-二聚体变化的研究[J].科学技术与工程,2009,9(15). |
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| 作者姓名： | 张冬青 汪德清 |
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| 作者单位： | 中国人民解放军总医院,北京,100853 |
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| 摘 要： | 观察大鼠自由进食高脂类食物后的血液流变及D-二聚体定性指标的变化趋势.选择大鼠随机分组,喂食高脂类食物,分别在10d、30d、60d、90d采静脉血抗凝,以全自动血液流变快测仪检测血粘度指标,免疫凝集法作D-二聚体定性检测.进食高脂类食物初期,大鼠的全血高切粘度指标呈显著下降,纤维蛋白原呈显著升高;持续进食高脂类食物后,全血粘度指标开始平稳上升,红细胞变形指数下降,60d、90d组中个别大鼠血浆D-二聚体检测出现阳性,提示大鼠血循环系统可能有血栓形成.平衡的脂肪类供给对大鼠的正常生理功能有益,而长期进食高脂类食物将对大鼠的生理功能产生强烈的负作用.
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| 关 键 词： | 高脂 血液流变学 D-二聚体 |
The Study of the Blood Viscocity and D-dimer Changes in Rats after Fed with High-fat Food Freely |
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| ZHANG Dong-qing,WANG De-qing.The Study of the Blood Viscocity and D-dimer Changes in Rats after Fed with High-fat Food Freely[J].Science Technology and Engineering,2009,9(15). |
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| Authors: | ZHANG Dong-qing WANG De-qing |
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| Institution: | Clinical Laboratory Department;First Affiliated Hospital of General Hospital of PLA;Beijing 100037;P.R.China |
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| Abstract: | To investigate the changing trend of the rat's hemorheology indexes and D-dimer qualitative markers after being fed with high-fat food. After being selected and divided into groups randomly,the rats were fed with high-fat food,then their venous anticoagulant blood samples were collected in 10 d,30 d,60 d,90 d respectively.The hemorheology indexes were detected with automatic hemorheology test equipment and D-dimer was tested with immune coagulation. In the initial stage after fed with high-lipid food,the ra... |
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| Keywords: | high-fat hemorheology D-dimer |
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