| 表面等离子共振检测葡萄糖浓度的数据处理方法 |
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| 引用本文： | 黄福祥,栗大超,伍鹏,张晶鑫,宋冰,徐可欣.表面等离子共振检测葡萄糖浓度的数据处理方法[J].天津大学学报(自然科学与工程技术版),2011,44(1). |
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| 作者姓名： | 黄福祥 栗大超 伍鹏 张晶鑫 宋冰 徐可欣 |
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| 作者单位： | 天津大学精密测试技术及仪器国家重点实验室; |
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| 基金项目： | 国家自然科学基金资助项目(30800239,30700146); 天津市应用基础与前沿技术研究计划资助项目(06YFGDGX17400); 高等学校博士学科点专项科研基金资助项目(20070056075,20070056076) |
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| 摘 要： | 根据表面等离子共振(SPR)检测葡萄糖浓度时信号和噪声的特点,研究了寻找曲线最低点算法和基线动态调整方法等SPR数据后处理方法.采用加权质心法精确地捕获到了表面等离子共振曲线的最低点,采用固定计算点数的动态基线法调整基线位置,消除了基线附近点值的波动对测量结果的影响.模拟仿真及实验验证结果表明,采用固定点数的动态基线法和加权质心法处理SPR数据,能显著提高SPR检测葡萄糖的分辨率,在葡萄糖浓度检测技术中有很好的应用前景.
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| 关 键 词： | 表面等离子共振 动态基线法 加权质心法 葡萄糖检测 |
Data Analysis Method for Glucose Detection Based on Surface Plasmon Resonance |
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| HUANG Fu-xiang,LI Da-chao,WU Peng,ZHANG Jing-xin,SONG Bing,XU Ke-xin.Data Analysis Method for Glucose Detection Based on Surface Plasmon Resonance[J].Journal of Tianjin University(Science and Technology),2011,44(1). |
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| Authors: | HUANG Fu-xiang LI Da-chao WU Peng ZHANG Jing-xin SONG Bing XU Ke-xin |
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| Institution: | HUANG Fu-xiang,LI Da-chao,WU Peng,ZHANG Jing-xin,SONG Bing,XU Ke-xin(State Key Laboratory of Precision Measuring Technology and Instruments,Tianjin University,Tianjin 300072,China) |
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| Abstract: | In this paper,according to the characteristics of the output signal and noise of surface plasmon reso-nance(SPR) system,weigh-centroid algorithm was applied to catch the minimum point of surface plasmon resonance curve and the method of dynamic baseline with fixed calculation points was used to eliminate the fluctuation of sur-face plasmon resonance curve.Simulation and experiment results show that the dynamic baseline method and weigh-centroid algorithm can improve the resolution of SPR system,which has go... |
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| Keywords: | surface plasmon resonance dynamic baseline method weigh-centroid algorithm glucose detection |
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