首页 | 本学科首页   官方微博 | 高级检索  
     检索      

红树内生真菌BYY-1中一个酚类化合物的分离鉴定与抗肿瘤活性
引用本文:杜希萍,赵保兵,郑忠辉,徐庆妍,苏文金.红树内生真菌BYY-1中一个酚类化合物的分离鉴定与抗肿瘤活性[J].集美大学学报(自然科学版),2011(6):424-428.
作者姓名:杜希萍  赵保兵  郑忠辉  徐庆妍  苏文金
作者单位:集美大学生物工程学院;厦门市食品生物工程技术研究中心;厦门大学生命科学学院;细胞生物学与肿瘤细胞工程教育部重点实验室;福建省药物工程实验室;
基金项目:中央高校基本业务费资助项目(2010121092); 福建省科技计划重点项目(2011N1008); 集美大学博士启动基金资助项目(ZQ2011004)
摘    要:采用硅胶柱层析、薄层层析、Sephadex LH-20柱层析从红树内生真菌BYY-1的次级代谢产物中分离到化合物B1.通过乙酰化、NMR、HR ESI-Q-TOF MS等技术鉴定了化合物B1的结构,确定其为首次从红树内生真菌中分离到的化合物.运用MTT法和流式细胞术研究了化合物B1的抗肿瘤活性,结果表明,化合物B1可显...

关 键 词:红树  真菌  分离鉴定  抗肿瘤活性

Study on the Isolation Identification and Antitumor Activity of a Phenol Derivative from Mangrove Fungus BYY-1
DU Xi-ping,ZHAO Bao-bing,,ZHENG Zhong-hui,XU Qing-yan,SU Wen-jin,.Study on the Isolation Identification and Antitumor Activity of a Phenol Derivative from Mangrove Fungus BYY-1[J].the Editorial Board of Jimei University(Natural Science),2011(6):424-428.
Authors:DU Xi-ping    ZHAO Bao-bing      ZHENG Zhong-hui  XU Qing-yan  SU Wen-jin  
Institution:DU Xi-ping1,2,ZHAO Bao-bing3,4,5,ZHENG Zhong-hui3,XU Qing-yan3,SU Wen-jin1,3,5(1.School of Biotechnology Engineering,Jimei University,Xiamen 361021,China,2.Food Bio-engineering Research Center of Xiamen,3.School of Life Science,Xiamen University,Xiamen 361005,4.Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering,5.Fujian Engineering Laboratory for Pharmaceuticals,China)
Abstract:Compound B1 was obtained from the secondary metabolites of mangrove fungus BYY-1 using silica gel column chromatography,thin layer chromatography and Sephadex LH-20 column chromatography.The structure of compound B1 was elucidated by acetylation,NMR and HR ESI-Q-TOF MS analysis,and compound B1 was isolated from mangrove fungi for the first time.The antitumor activity of compound B1 was studied by the methods of MTT and flow cytometric DNA analysis.The results showed compound B1 could significantly inhibit t...
Keywords:mangrove  fungi  isolation identification  antitumor activity  
本文献已被 CNKI 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号