电子束及紫外线对动物红血细胞膜损伤的研究

电子静电加速器所产生的电子束及紫外线对豚鼠及黄鳝红血细胞膜的损伤程度是随照射剂量的增加而加大,在相同的剂量下,豚鼠红血细胞对射线的损伤效应比黄鳝敏感。电子束辐照红血细胞后加以短时间的紫外线照射,加剧了细胞膜的损伤。应用一定浓度的广辐-1号保护剂对两种动物的红血细胞进行预处理,对于一定剂量的电子束和紫外线的照射均能起明显的辐射保护作用。本实验还证明保护剂广辐—1号与红血细胞膜的透性无关,它不能促进~(32)P掺入细胞内。

Studies on the Damages Caused by Electron Beam and Ultraviolet Light to Cell Mambrance of Erythrocytes

The damages caused by electron beam (produced by electrostatic accelerator)and Ultraviolet light to the cell mambrance of erythrocytes of Cavia porceliaand Monopterus albus as well as the radioprotective actions were studied. Under the experimental conditions the degree of damages the cell mambranceof erythrocytes increased as the doses increased. Cell mambrance of erythrocytesof Cavia porcelia was more sensitive to the damage effect of radiation than thatof Monopterus albus when treated with the same dose. The experiment showed that after being exposed to electron beam a shorttime of irradiation of Ultraviolet light could increase the damage of cell mambr-ance. It also showed that there was an obvious radioprotective action under cer-tain dose of irradiation of electron beam and ultraviolet light when the erythro-cytes were pretreated with certain concentration of the protector GUANGFU-1. The experiment proved that the protector GUANGFU-1 had no thing to dowith the penetrativity of cell mambrance of erythrocytes. It could not promotethe incorporation of ~(32)P into cells.