| 心肌宁冲剂长期毒性试验研究 |
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| 引用本文： | 崔新颖,吕俊华,王北辰,张成义,崔新羽,孙敏,吴玉华,李保玉.心肌宁冲剂长期毒性试验研究[J].北华大学学报(自然科学版),1995(4). |
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| 作者姓名： | 崔新颖 吕俊华 王北辰 张成义 崔新羽 孙敏 吴玉华 李保玉 |
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| 作者单位： | 吉林医学院药理教研室
(崔新颖，吕俊华，王北辰，张成义)，吉林医学院血液检验教研室
(崔新羽，孙敏)，吉林医学院附院检验科
(吴玉华)，吉林医学院病理教研室(李保玉) |
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| 摘 要： | 心肌宁冲剂按相当成人日用量的70倍和35倍(即7g/kg/日和3.5g/kg/日)。大白鼠60只连续伺服8周,每周称重一次。并观察动物活动,毛发粪便情况,用药结束后,每组取10只动物,采血检查血常规,肝肾功能,取重要脏器进行病理组织学检查,结果未见明显毒性。
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| 关 键 词： | 心肌宁冲剂 血常规 肝肾功能 |
The Study on Long-term Toxicity Test for Xin jining Chongji |
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| Cui Xinying et al.The Study on Long-term Toxicity Test for Xin jining Chongji[J].Journal of Beihua University(Natural Science),1995(4). |
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| Authors: | Cui Xinying |
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| Institution: | Department of Pharmacology |
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| Abstract: | Xin Jining Chongji was given to rats(60 rats divided into 2 drug groups and 1 control group) according to 70 times and 35 times of adult human dosage( i.e. 7g/kg/day and 3. 5g/ kg/day) for 8 consecutive weeks. Rats were weighted once every week with their activities and conditions of hair and feces observed. At the end of drugadministration, 10 rats were taken from each group for exam on blood routine, liver and kidney functions, and pathohistological exam of important viscera. No evident toxicily was found in the above exam. |
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| Keywords: | Xin Jining Choagji Blood routine Liver and kidney functions |
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