| 大豆皂甙对S_(180)腹水肉瘤细胞超微结构及表面电荷的影响 |
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| 引用本文： | 陈静,陈建光,王鹏,郁利平.大豆皂甙对S_(180)腹水肉瘤细胞超微结构及表面电荷的影响[J].北华大学学报(自然科学版),1999(1). |
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| 作者姓名： | 陈静 陈建光 王鹏 郁利平 |
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| 作者单位： | 吉林医学院预防医学系!吉林132001(陈静)，吉林医学院药理教研室(陈建光)，吉林省防疫站(王鹏)，白求恩医科大学预防医学院营养卫生教研室(郁利平) |
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| 摘 要： | 目的：通过研究TS对S180腹水肉瘤细胞超微结构及表面电荷的影响，探讨了TS抗癌作用机理。方法：采用细胞电泳测定法和电子显微镜观察法。结果：TS可破坏S180肿瘤细胞超微结构，使其细胞膜微绒毛变粗短，数量减少，线粒体肿胀；TS可使S180肿瘤细胞电泳率下降。结论：表明TS对S180肿瘤细胞有直接杀伤作用。
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| 关 键 词： | 大豆皂甙 S_(180)细胞 超微结构 表面电荷 |
The effects of total soyasoponin on the ultrastructure and surface charge of S_(180) ascites sarcoma cells |
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| Chen Jing, Chen Jianguang, Wang Peng, Yu Liping.The effects of total soyasoponin on the ultrastructure and surface charge of S_(180) ascites sarcoma cells[J].Journal of Beihua University(Natural Science),1999(1). |
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| Authors: | Chen Jing Chen Jianguang Wang Peng Yu Liping |
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| Institution: | Jilin Medical College Jilin City 132001 |
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| Abstract: | Objective: To study the anti - cancer mechanism of total soyasoponin(TS) by examining its essects on the ultrastructure and surface charge of S180 ascites sarcoma cells. Methods: cell electrophoresis and eletromicroscope. Result: TS damaged the ultrastructure of S180 cancer cells, shortened and thickened the microvillus, swelled mitochondria. TS also decreased electrophoresis rate of S180 cell. Conclusion: TS has direct killing effects on S180 cells. |
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| Keywords: | Total soyasoponin S_(180) cell ultrastructure surface charge |
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