心绞痛患者经PCI治疗后不良心脏事件与血清总胆红素水平相关性分析

目的分析心绞痛患者经PCI治疗后不良心脏事件与血清总胆红素水平的相关性.方法选取行PCI的129例心绞痛患者,根据血清TBIL水平将患者分为对照组和观察组,比较两组患者实验室检查指标;比较分析两组患者冠状动脉造影检查结果;比较分析两组患者行PCI的相关指标;比较两组患者发生不良心血管事件(MACE)的情况,并进行Cox比例风险回归分析.结果观察组患者TG,TC水平高于对照组,差异具有统计学意义(P0.05),而其余指标(血糖、Scr、Hb、LDL-C、HDL-C、AST)两组患者比较差异无统计学意义(P0.05);观察组患者冠状动脉病变支数、靶病变部位、慢性闭塞病变及LVEF≤40%与对照组比较差异均无统计学意义(P0.05);观察组患者置入支架长度长于对照组,差异具有统计学意义(P0.05);两组患者经桡动脉途径行PCI者所占比例、置入支架数和置入支架直径与对照组比较,差异无统计学意义(P0.05);术后观察组患者随访期间MACE发生率为24.1%,高于对照组的8.4%,差异具有统计学意义(P0.05);Cox比例风险回归分析结果显示:血清TBIL水平是心绞痛患者PCI后MACE的保护因素,置入支架长度则是危险因素.结论心绞痛患者PCI后血清TBIL水平越低其预后越差;血清TBIL水平是心绞痛患者PCI后MACE的保护因素,置入支架长度则是危险因素.

Correlation between Adverse Cardiac Events and Serum Total Bilirubin Levels in Patients with Angina Pectoris after PCI Treatment

Objective To analyze the correlation between the adverse cardiac events and serum total bilirubin levels in patients with angina pectoris after PCI treatment. Method 129 patients with angina pectoris were enrolled. According to the serum level of TBIL, patients were divided into control group and observation group, compared patients with laboratory indexes of two groups;compared patients with coronary artery angiography of two groups;compared patients underwent PCI of two groups;compared patients with adverse cardiovascular events (MACE) of two groups and Cox proportional hazards regression analysis. Results TC and TG level in the observation group were higher than those of the control group,the difference was statistically significant (P<0. 05);and the rest indexes ( blood glucose,Scr,Hb,LDL-C,HDL-C,AST) were compared between the two groups,there was no statistically significant difference ( P>0. 05 );to observe the difference between the groups of patients with coronary artery lesions and target lesion location,chronic occlusion and LVEF is less than or equal to 40％ and the control group had no statistical significance (P>0. 05);patients with stent length of the observation group are longer than those of the control group,the difference was statistically significant (P<0. 05);two groups with transradial PCI proportion, stent and stent diameter compared with the control group,the difference was not statistically significant (P>0. 05);postoperative patients in the observation group during the follow-up period, the incidence rate of MACE was 24. 1％,higher than 8. 4％ in the control group,the difference was statistically significant (P<0. 05). The results of regression analysis showed that serum TBIL level was the protective factor of MACE in patients with angina pectoris after PCI,and the length of stent implantation was a risk factor. Conclusion The lower the level of serum TBIL in patients with angina pectoris,the worse the prognosis is. The serum level of TBIL is the protective factor of PCI after PCI in patients with angina pectoris,and the length of stent implantation is a risk factor for MACE.