Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria |
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| Authors: | M Y Cheng F U Hartl J Martin R A Pollock F Kalousek W Neupert E M Hallberg R L Hallberg A L Horwich |
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| Institution: | Yale University School of Medicine, Department of Human Genetics, New Haven, Connecticut 06510. |
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| Abstract: | A nuclear encoded mitochondrial heat-shock protein hsp60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. hsp60 is a member of the 'chaperonin' class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts. |
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