| 兔骨髓间充质干细胞复合脱细胞牛松质骨体外相容性研究 |
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| 引用本文： | 刘维钢,张永刚,王德超,郭亚梅,史晨辉,董金波.兔骨髓间充质干细胞复合脱细胞牛松质骨体外相容性研究[J].石河子大学学报,2006,24(3):316-320. |
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| 作者姓名： | 刘维钢 张永刚 王德超 郭亚梅 史晨辉 董金波 |
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| 作者单位： | [1]石河子大学医学院第一附属医院,新疆石河子832008 [2]大连医科大学第二附属医院,辽宁大连116002 |
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| 摘 要： | 探讨脱细胞牛松质骨（Acellular Bovince Cancellous Bone，ABcB）生物衍生材料与骨髓间充质干细胞（bone marrow mesenchymal stem cells，BMSCs）的生物相容性，为组织工程方法修复骨缺损提供依据。将兔骨髓间充质干细胞与ABCB复合并体外培养，然后进行形态学、细胞增殖、蛋白质含量测定。骨髓间充质干细胞能够贴附在ABCB孔隙内生长，细胞生长及蛋白合成功能不受ABCB的影响。ABCB生物相容性良好，可作为组织工程的支架材料应用于骨缺损的修复；BMSCs可以作为骨组织工程种子细胞。
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| 关 键 词： | 脱细胞牛松质骨 骨髓间充质干细胞 生物相容性 骨组织工程 |
| 文章编号： | 1007-7383（2006）03-0316-05 |
| 收稿时间： | 2006-03-04 |
| 修稿时间： | 2006年3月4日 |
Biocompatibility of Acellular Bovince Cancellous Bone with Co-cultured Bone Marrow Mesenchymal Stem Cells |
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| LIU Wei-gang, ZHANG Yong-gang, WANG De-chao, SHI Chen-hui, DONG Jin-bo.Biocompatibility of Acellular Bovince Cancellous Bone with Co-cultured Bone Marrow Mesenchymal Stem Cells[J].Journal of Shihezi University(Natural Science),2006,24(3):316-320. |
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| Authors: | LIU Wei-gang ZHANG Yong-gang WANG De-chao SHI Chen-hui DONG Jin-bo |
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| Abstract: | To study the biocompatibility of Acellular Bovince Cancellous Bone(ABCB)With co-cultured bone marrow mesenchymal stem cells(BMSCs) in vitro.BMSCs were seeded into ABCB and cultured in vitro,then their morphological characteristics,growth curve and proliferation,protein centent were detected.BMSCs could attach to the inner surface of ABCB,and their capability of protein production were not affected by ABCB.ABCB has good Biocompatibility and can provide suitable space for BMSCs.It can be used to repair bone defects as scafflold in bone tisse engineering;BMSCs is a kind of seed cell in bone tisse engineering. |
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| Keywords: | Acellular Bovince Cancellous Bone bone marrow mesenchymal stem cells biocompatibility bone tisse engineering |
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