| 注射H5N1亚型禽流感抗体鸡的血清抗体水平消长规律监测 |
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| 引用本文： | 赵福江,任艳,李红梅,魏艳丽.注射H5N1亚型禽流感抗体鸡的血清抗体水平消长规律监测[J].山东科学,2007,20(5):32-34. |
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| 作者姓名： | 赵福江 任艳 李红梅 魏艳丽 |
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| 作者单位： | 山东省科学院生物研究所,山东,济南,250014 |
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| 摘 要： | 为了解H5N1亚型禽流感纯化抗体(IgG)在鸡体内消长规律,用血凝抑制试验检测了不同注射时间分离的血清样品。结果表明IgG接种后第1至5天,血清抗体滴度恒定在24~26,第8天为23~24,第10天以后几乎检测不到抗体。上述数据表明注射滴度为29的抗体液1mL可有效保护肉鸡免受禽流感病毒的感染,有效期为8天。
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| 关 键 词： | HSN1亚型禽流感 抗体 消长规律 |
| 文章编号： | 1002-4026（2007）05-0032-03 |
| 收稿时间： | 2007-05-15 |
Detection on the Level of Sera Antibodies from Chicken Injected by Antibodies against Avian Influenza Virus H5N1 Subtype |
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| ZHAO Fu-jiang,REN Yan,LI Hong-mei,WEI Yan-li.Detection on the Level of Sera Antibodies from Chicken Injected by Antibodies against Avian Influenza Virus H5N1 Subtype[J].Shandong Science,2007,20(5):32-34. |
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| Authors: | ZHAO Fu-jiang REN Yan LI Hong-mei WEI Yan-li |
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| Institution: | Institute of Biology, Shandong Academy of Sciences, Jinan 250014, China |
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| Abstract: | In order to investigate the metabolism law of antibodies against Avian influenza virus H5N1 subtype(An-AIV-H5N1),we detected sera samples collected at different time in antibody-injected chicken by hemagglutinin inhibitory test(HI). It is shown that the HI level of sera antibodies sustains from 24 to 26 within 5 days after injection,and from 23 to 24 on the 8th days after injection,and that level of antibody can hardly be detected after 10 days from injection.The result shows that An-AIV-H5N1 can effectively protect edible chicken from the infection of AIV-H5N1 when the 29 HI titer and 1mL dose are used in them,and that the effective protection term is 8 days after injection. |
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| Keywords: | avian influenza H5N1 subtype antibody law of disappearance |
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