| 健坤胶囊渗漉提取工艺研究 |
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| 引用本文： | 丁小艳,游本刚,江帆,杨世林.健坤胶囊渗漉提取工艺研究[J].贵州师范大学学报(自然科学版),2014,32(5):116-120. |
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| 作者姓名： | 丁小艳 游本刚 江帆 杨世林 |
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| 作者单位： | 1. 贵州省山地环境信息系统与生态环境保护重点实验室,贵州师范大学分析测试中心,贵州贵阳550001
2. 苏州大学药学院,江苏苏州,215123 |
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| 基金项目： | 贵州省中药现代化科技产业研究开发专项，贵阳市科学技术计划项目 |
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| 摘 要： | 目的:筛选健坤胶囊渗漉提取工艺条件。方法:以白头翁皂苷B4、盐酸小檗碱、蛇床子素等的转移率为评价指标,采用单因素平行设计及多因素正交设计方法逐级优化健坤胶囊提取工艺。结果:最佳渗漉工艺条件为:30倍量70%乙醇,浸渍24h,流速为0.5mL/min。结论:该提取工艺稳定、重现性好,可作为本品的提取方法。
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| 关 键 词： | 健坤胶囊 渗漉提取 转移率 正交试验 |
Extraction technology of Jiankun granules |
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| DING Xiaoyan,YOU Bengang,JIANG Fan,YANG Shilin.Extraction technology of Jiankun granules[J].Journal of Guizhou Normal University(Natural Sciences),2014,32(5):116-120. |
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| Authors: | DING Xiaoyan YOU Bengang JIANG Fan YANG Shilin |
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| Institution: | DING Xiaoyan;YOU Bengang;JIANG Fan;YANG Shilin;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment,Guizhou Normal University;School of Pharmacy,Soochow University Suzhou University; |
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| Abstract: | Objective：To optimize percolation extraction process conditions of Jiankun capsules.Methods：The transfer rate of several main components as evaluation index,preliminary selected extraction process route.The orthogonal experiments were designed for the percolation process of Jiankun capsules.Results：The optimal extraction process was established as follows,the materials were soaking for 24h,percolated at the rate of 0.5mL/min with 30 times amount of 70％ alcohol.Conclusions：the extraction technology is stable,reliable,reproducible,and feasible. |
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| Keywords: | Jiankun capsules percolation extraction transfer rate orthogonal experiments |
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