| β-环糊精在复方姜黄片制剂工艺中的应用 |
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| 引用本文： | 王瑞,邹贵田,徐宏.β-环糊精在复方姜黄片制剂工艺中的应用[J].贵州师范大学学报(自然科学版),2006,24(1):60-63. |
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| 作者姓名： | 王瑞 邹贵田 徐宏 |
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| 作者单位： | 1. 贵阳学院,工程技术系,贵州,贵阳,550003
2. 贵州省药品检验所,生测室,贵州,贵阳,550002 |
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| 摘 要： | 通过正交实验法,优选出最佳包合工艺为姜黄提取物与β-环糊精投料比为1∶4,使用20%的乙醇溶液为溶媒,30℃下搅拌1.5h。经高效液相法测定,此工艺可以减少姜黄素在制剂工艺过程中的损失。
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| 关 键 词： | 减少损失 β-环糊精 姜黄素 制备工艺 |
| 文章编号： | 1004-5570（2006）01-0060-04 |
| 收稿时间： | 2005-03-24 |
| 修稿时间： | 2005年3月24日 |
Application of β-cyclodextrin for preparation process of compound Jianghuang tablets |
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| WANG Rui,ZOU Gui-tian,XU Hong.Application of β-cyclodextrin for preparation process of compound Jianghuang tablets[J].Journal of Guizhou Normal University(Natural Sciences),2006,24(1):60-63. |
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| Authors: | WANG Rui ZOU Gui-tian XU Hong |
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| Institution: | 1. Department of Engineering, Guiyang Institute, Guiyang, Guizhou 550003, China; 2. Guizhou Institute for Drug Control, Guiyang, Guizhou 550002, China |
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| Abstract: | The study was carried out with orthogonal design.The optimun preparation conditions for inclusion as extractive : β-CD was 1∶4.The inclusion temperature was 30℃ and time was 1.5h.The consistence of ethanol is 20%.HPLC is used.The technics can reduce the loss of curcumin in preparation process. |
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| Keywords: | reduce the loss β-cyclodextrin curcumin preparation |
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