| 紫外一阶导数光谱法测定安定血药浓度 |
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| 引用本文： | 刘布鸣,吴雁,蒋瑾华,钟正贤.紫外一阶导数光谱法测定安定血药浓度[J].广西科学,1996,3(4):15-17. |
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| 作者姓名： | 刘布鸣 吴雁 蒋瑾华 钟正贤 |
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| 作者单位： | 广西中医药研究所，桂林医学院药学系 |
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| 摘 要： | 用紫外一阶导数光谱法，消除生物样品的背景干扰，简化分析过程，建立了安定血药浓度的测定方法。
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| 关 键 词： | 血药浓度 安定镇静药 紫外光谱法 测定 |
| 收稿时间： | 1996/8/6 0:00:00 |
Determination of Diazepam in Blood by UV First Derivative Spectroscopy |
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| Liu Buming,Wu Yan,Jiang Jinhua and Zhong Zhengxian.Determination of Diazepam in Blood by UV First Derivative Spectroscopy[J].Guangxi Sciences,1996,3(4):15-17. |
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| Authors: | Liu Buming Wu Yan Jiang Jinhua and Zhong Zhengxian |
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| Institution: | Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20 Gucheng Road, Nanning, Guangxi, 530022,Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20 Gucheng Road, Nanning, Guangxi, 530022,Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20 Gucheng Road, Nanning, Guangxi, 530022 and Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20 Gucheng Road, Nanning, Guangxi, 530022 |
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| Abstract: | The interference from background of biological materials was partially eliminated and analytical process simplified was made by using UV first derivative spectroscopy.This paper reports a study on the method for the determination of diazepam in plasma and determining the original drug in biological fluid after intravenous diazepam by using the method. The determined results were used to study the pharmacokinetics of diazepam. |
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| Keywords: | UV first derivative spectroscopy diazepam drug concentration in plasma |
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